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Rare Neurovascular Diseases in Korea: Classification and Related Genetic Variants

Song Y, Kwon B, Al-Abdulwahhab AH, Nam YK, Ahn Y, Jeong SY, Seo EJ, Lee JK, Suh DC

Rare neurovascular diseases (RNVDs) have not been well-recognized in Korea. They involve the central nervous system and greatly affect the patients’ lives. However, these diseases are difficult to diagnose and...
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Deep Learning-Based Artificial Intelligence for Mammography

Yoon JH, Kim EK

During the past decade, researchers have investigated the use of computer-aided mammography interpretation. With the application of deep learning technology, artificial intelligence (AI)-based algorithms for mammography have shown promising results...
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Diagnosis of Hypersensitivity Pneumonitis: 2020 Clinical Practice Guideline

Park S, Oh YW, Kang EY, Yong HS, Kim C, Lee KY, Hwang SH

Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) characterized by an inhaled inciting antigen that leads to the inflammation of the lung parenchyma and small airway with immunologic reactions....
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Evaluation and diagnosis of neuropathic pain

Oh J

Background: Thorough evaluation and an accurate diagnosis of neuropathic pain are essential for effective treatment. The therapeutic approach and choice of medication for neuropathic pain are different from those for...
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Standardization of the pathologic diagnosis of appendiceal mucinous neoplasms

Kang DW, Kim Bh, Kim JM, Kim J, Chang HJ, Chang MS, Sohn JH, Cho MY, Jin SY, Chang HK, Han HS, Kim JY, Kim HS, Park DY, Park HY, Lee SJ, Lee W, Lee HS, Kang YN, Choi Y, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

Although the understanding of appendiceal mucinous neoplasms (AMNs) and their relationship with disseminated peritoneal mucinous disease have advanced, the diagnosis, classification, and treatment of AMNs are still confusing for pathologists...
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Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center Experience

Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K

Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of...
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Evaluating an In-House Cell-Based Assay for Detecting Antibodies Against Muscle-Specific Tyrosine Kinase in Myasthenia Gravis

Kim MJ, Kim SW, Kim M, Choi YC, Kim SM, Shin HY

Background and Purpose Detecting antibodies against muscle-specific tyrosine kinase (MuSK Abs) is essential for diagnosing myasthenia gravis (MG). We applied an in-house cellbased assay (CBA) to detect MuSK Abs. Methods A...
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Development of the Parental Questionnaire for Cerebral Visual Impairment in Children Younger than 72 Months

Moon JH, Kim GH, Kim SK, Kim S, Kim YH, Kim J, Kim JK, Noh BH, Byeon JH, Yeom JS, Eun BL, Eun SH, Choi J, Chung HJ

Background and Purpose: Cerebral visual impairment (CVI) is an underdiagnosed condition in children, and its assessment tools have focused on older children. We aimed to develop a parental questionnaire for...
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KASL clinical practice guidelines: Management of nonalcoholic fatty liver disease

Kang SH, Lee HW, Yoo JJ, Cho Y, Kim SU, Lee TH, Jang BK, Kim SG, Ahn SB, Kim H, Jun DW, Choi JI, Song DS, Kim W, Jeong SW, Kim MY, Koh H, Jeong S, Lee JW, Cho YK, The Korean Association for the Study of the Liver (KASL)

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The Similarity of Biomarkers Level between Direct Nasal Fluid and Nasal Lavage Fluid in Allergic Rhinitis Patients

Kim JS, Han SJ, Park JM, Kim SW, Eun YG, Kwon OE

Background and Objectives: Biomarkers of allergic rhinitis (AR) have been studied; however, little is known regarding their practical application in the diagnosis of AR. Previous studies collected samples using saline...
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Diagnostic Accuracy of the Quidel Sofia Rapid Influenza Fluorescent Immunoassay in Patients with Influenza-like Illness: A Systematic Review and Meta-analysis

Lee J, Song JU, Kim YH

Background: Although the Quidel Sofia rapid influenza fluorescent immunoassay (FIA) is widely used to identify influenza A and B, the diagnostic accuracy of this test remains unclear. Thus, the objective...
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Diagnostic Performance of 2018 KLCA-NCC Practice Guideline for Hepatocellular Carcinoma on Gadoxetic Acid-Enhanced MRI in Patients with Chronic Hepatitis B or Cirrhosis: Comparison with LI-RADS Version 2018

Lee SM, Lee JM, Ahn SJ, Kang HJ, Yang HK, Yoon JH

Objective: To evaluate the performance of the 2018 Korean Liver Cancer Association-National Cancer Center (KLCA-NCC) Practice Guidelines (hereafter, PG) for the diagnosis of hepatocellular carcinoma (HCC) using gadoxetic acid-enhanced MRI,...
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Serum milk fat globule-EGF factor 8 protein as a potential biomarker for metabolic syndrome

Lee HA, Lim J, Joo HJ, Lee YS, Jung YK, Kim JH, An H, Yim HJ, Jeen YT, Yeon JE, Lim DS, Byun KS, Seo YS

Background/Aims: Useful biomarkers for metabolic syndrome have been insufficient. We investigated the performance of serum milk fat globule-EGF factor-8 (MFG-E8), the key mediator of inflammatory pathway, in diagnosis of metabolic...
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The diagnosis of an imperforate anus in female fetuses

Kim HM, Cha HH, Kim JI, Seong WJ, Park SH, Kim MJ

Imperforate anus is an anomaly caused by a defect in the development of the hindgut during early pregnancy. It is a relatively common congenital malformation and is more common in...
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Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis

Son JH, Lee JU, Chin S, Go ES, Park JS, Shin HK, Chang HS, Park JS, Park CS

Background/Aims: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a major regulator of Wnt signaling, which is involved in fibroblast dysfunction. Because its role has not been evaluated in idiopathic...
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Diagnostic Approach to the Suspected Cases of Hereditary Spastic Paraplegia

Choi SJ, Sung JJ

Hereditary spastic paraplegia (HSP) is a heterogeneous group of monogenic neurodegenerative disorders characterized by progressive spasticity of the lower limbs. The clinical features and imaging abnormalities vary greatly according to...
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Evaluation of Rapid IgG4 Test for Diagnosis of Gnathostomiasis

Wang Y, Ma A, Liu XL, Eamsobhana P, Gan XX

Human gnathostomiasis is a parasitic disease caused by Gnathostoma nematode infection. A rapid, reliable, and practical immunoassay, named dot immuno-gold filtration assay (DIGFA), was developed to supporting clinical diagnosis of...
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A Case of Adenocarcinoma Developed in the Terminal Ileum Presenting Elevated Carcinoembryonic Antigen

Lee SH, Lee JG

Malignant neoplasm of the small intestine is a relatively rare disease. Because the early manifestation of symptoms in patients with cancer of the small intestine is non-specific, diagnosis is often...
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Subclinical Hypothyroidism: Prevalence, Health Impact, and Treatment Landscape

Yoo WS, Chung HK

Subclinical hypothyroidism (sHypo) is defined as normal serum free thyroid hormone levels coexisting with elevated serum thyroid-stimulating hormone (TSH) levels. sHypo is a common condition observed in clinical practice with...
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Diagnosis and treatment of pediatric type 2 diabetes mellitus

Lee HS

Background: Type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic diseases, and its increasing prevalence in children and adolescents is a worldwide problem. In the past ten...
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