Korean J Thorac Cardiovasc Surg.  1997 Aug;30(8):752-759.

Clinical Application of Compressed Spectral Array During Deep Hypothermia

• Chan BC
• Yoo SK
• Kim SH
• Song JS
• Park SJ
• Moon JH
• Kim JT
• Kwak YL
• Hong YW

Abstract

Profound hypothermia protects cerebral function during total circulatory arrest(TCA) in the surgical treatment of a variety of cardiac and aortic diseases. Despite its importance, there is no ideal technique to monitor the brain injury from ischemia. Since 1994, we have developed compressed spectral array(CSA) of electroencephalography(EEG) and monitored cerebral activity to reduce ischemic injury. The purposes of this study are to analyse the efficacy of CSA and to establish objective criteria to consistently identify the safe level of temperature and arrest time. We studied 6 patients with aortic dissection(AD, n=3) or aortic arch aneurysm(n=3, ruptured in 2). Body temperatures from rectum and esophagus and the EEG were monitored continuously during cooling and rewarming period. TCA with cerebral ischemia was performed in 3 patients and TCA with selective cerebral perfusion was performed in 3 patients. Total ischemic time was 30, 36 and 56 minutes respectively for TCA group and selective perfusion time was 41, 56 and 92 minutes respectively for selective perfusion group. The rectal temperatures for flat EEG were between 16.1 and 22.1 degrees C (mean:18.4+/-2.0); the esophageal temperatures between 12.7 and 16.4 degrees C(mean : 14.7+/-1.6). The temperatures at which EEG reappeared 5~15.4 degrees C for esophagus. There was no neurological deficit and no surgical mortality in this series. In summary, the electrical cerebral activity reappeared within 23 minutes at the temperature less than 16degrees C for rectum. It seemed that 15 degrees C of esophageal temperature was not safe for 30 minutes of TCA and continuous monitoring the EEG with CSA to identify the electrocerebral silence was useful.

Keyword

Total circulatory arrest, induced; Hypothermia, induced; Brain injury; Electroencephalography

MeSH Terms

Aorta, Thoracic
Aortic Diseases
Body Temperature
Brain Injuries
Brain Ischemia
Electroencephalography
Esophagus
Humans
Hypothermia*
Hypothermia, Induced
Ischemia
Mortality
Perfusion
Rectum
Rewarming