- Platycarya strobilacea leaf extract protects mice brain with focal cerebral ischemia by antioxidative property
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Lee JH, Jeong JH, Jeong YG, Kim DK, Lee NS, Na CS, Doh ES, Han SY
- KMID: 2466703
- Anat Cell Biol.
- 2019 Dec;52(4):486-497.
- doi: 10.5115/acb.19.141
The leaf extract of Platycarya strobilacea (PSL) has long been recognized as possessing various health-promoting activities. However, information on its possible protective effects against ischemic stroke is currently lacking. Here,... -
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- Neuregulin 1/ErbB4 signaling attenuates neuronal cell damage under oxygen-glucose deprivation in primary hippocampal neurons
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Yoo JY, Kim HB, Yoo SY, Yoo HI, Song DY, Baik TK, Lee JH, Woo RS
- KMID: 2466700
- Anat Cell Biol.
- 2019 Dec;52(4):462-468.
- doi: 10.5115/acb.19.210
The hippocampus is one of the most important brain areas of cognition. This region is particularly sensitive to hypoxia and ischemia. Neuregulin-1 (NRG1) has been shown to be able to... -
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- Correlation between Carotid Arterial Calcium Score and Silent Cerebrovascular Lesions in Obstructive Sleep Apnea Patients: by Using Upper Airway CT and Brain MRI
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Kim MS, Kang EJ, Bae WY, Kim JK, Kim CH, Choi JH, Kim SH, Kim DY, Lee KN
- KMID: 2464918
- J Korean Soc Radiol.
- 2019 Nov;80(6):1214-1228.
- doi: 10.3348/jksr.2019.80.6.1214
PURPOSE: To investigate the relationship between carotid arterial calcium score (CarACS) and silent cerebrovascular lesions in patients with obstructive sleep apnea (OSA). MATERIALS AND METHODS: This study involved retrospective evaluation of... -
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- S1Pâ‚ Regulates M1/M2 Polarization toward Brain Injury after Transient Focal Cerebral Ischemia
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Gaire BP, Bae YJ, Choi JW
- KMID: 2462879
- Biomol Ther.
- 2019 Nov;27(6):522-529.
- doi: 10.4062/biomolther.2019.005
M1/M2 polarization of immune cells including microglia has been well characterized. It mediates detrimental or beneficial roles in neuroinflammatory disorders including cerebral ischemia. We have previously found that sphingosine 1-phospate... -
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- Resveratrol modulates the Akt/GSK-3β signaling pathway in a middle cerebral artery occlusion animal model
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Park DJ, Kang JB, Shah FA, Koh PO
- KMID: 2470008
- Lab Anim Res.
- 2019 Oct;35(3):124-131.
- doi: 10.1186/s42826-019-0019-8
Cerebral ischemia is a major cause of neurodegenerative disease. It induces neuronal vulnerability and susceptibility, and leads to neuronal cell death. Resveratrol is a polyphenolic compound that acts as an... -
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- History of Migraine and Volume of Brain Infarcts: The Italian Project on Stroke at Young Age (IPSYS)
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Giuli VD, Besana M, Grassi M, Zedde M, Zini A, Lodigiani , Marcheselli S, Cavallini , Micieli G, Rasura M, DeLodovici ML, Tomelleri , Checcarelli N, Chiti A, Giorli E, Sette MD, Tancredi L, Toriello A, Braga M, Morotti A, Poli L, Caria F, Gamba M, Patella R, Spalloni A, Simone AM, Pascarella R, Beretta S, Fainardi E, Padovani A, Gasparotti R, Pezzini A, the Italian Project on Stroke in Young Adults (IPSYS) Investigators
- KMID: 2464649
- J Stroke.
- 2019 Sep;21(3):324-331.
- doi: 10.5853/jos.2019.00332
BACKGROUND AND PURPOSE: Migraine has been shown to increase cerebral excitability, promote rapid infarct expansion into tissue with perfusion deficits, and result in larger infarcts in animal models of focal... -
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- The Role of Double Inversion Recovery Imaging in Acute Ischemic Stroke
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Choi NY, Park S, Lee CM, Ryu CW, Jahng GH
- KMID: 2459875
- Investig Magn Reson Imaging.
- 2019 Sep;23(3):210-219.
- doi: 10.13104/imri.2019.23.3.210
PURPOSE: The purpose of this study was to investigate if double inversion recovery (DIR) imaging can have a role in the evaluation of brain ischemia, compared with diffusion-weighted imaging (DWI)... -
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- Initial Experience of ACE68 Reperfusion Catheter in Patients with Acute Ischemic Stroke Related to Internal Carotid Artery Occlusion
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Jang HG, Park JS, Lee JM, Kwak HS
- KMID: 2457944
- J Korean Neurosurg Soc.
- 2019 Sep;62(5):545-550.
- doi: 10.3340/jkns.2019.0108
OBJECTIVE: Penumbra ACE68 reperfusion catheter is a new large bore aspiration catheter used for reperfusion of large vessel occlusion. The objective of this study was to investigate the efficacy of... -
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- Fully Automatic Segmentation of Acute Ischemic Lesions on Diffusion-Weighted Imaging Using Convolutional Neural Networks: Comparison with Conventional Algorithms
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Woo I, Lee A, Jung SC, Lee H, Kim N, Cho SJ, Kim D, Lee J, Sunwoo L, Kang DW
- KMID: 2453077
- Korean J Radiol.
- 2019 Aug;20(8):1275-1284.
- doi: 10.3348/kjr.2018.0615
OBJECTIVE: To develop algorithms using convolutional neural networks (CNNs) for automatic segmentation of acute ischemic lesions on diffusion-weighted imaging (DWI) and compare them with conventional algorithms, including a thresholding-based segmentation. MATERIALS... -
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- Efficacy of Combining Proximal Balloon Guiding Catheter and Distal Access Catheter in Thrombectomy with Stent Retriever for Anterior Circulation Ischemic Stroke
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Kim SH, Choi JH, Kang MJ, Cha JK, Kim DH, Nah HW, Park HS, Kim SH, Huh JT
- KMID: 2463671
- J Korean Neurosurg Soc.
- 2019 Jul;62(4):405-413.
- doi: 10.3340/jkns.2019.0007
OBJECTIVE: We evaluated efficacy of combining proximal balloon guiding catheter (antegrade flow arrest) and distal access catheter (aspiration at the site of occlusion) in thrombectomy for anterior circulation ischemic stroke. METHODS:... -
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- C3a Receptor Inhibition Protects Brain Endothelial Cells Against Oxygen-glucose Deprivation/Reperfusion
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Ahmad S, Kindelin A, Khan SA, Ahmed M, Hoda MN, Bhatia K, Ducruet AF
- KMID: 2450214
- Exp Neurobiol.
- 2019 Apr;28(2):216-228.
- doi: 10.5607/en.2019.28.2.216
The complement cascade is a central component of innate immunity which plays a critical role in brain inflammation. Complement C3a receptor (C3aR) is a key mediator of post-ischemic cerebral injury,... -
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- Predicting the Outcome of Critically Ill Children and Adolescents with Electroencephalography
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Lee S, Ko A, Sol IS, Kim KW, Kang HC, Lee JS, Kim HD, Kim SH
- KMID: 2449921
- Ann Child Neurol.
- 2019 Mar;27(1):13-21.
- doi: 10.26815/acn.2019.00010
PURPOSE: Electroencephalography (EEG) is an effective test in predicting severe cortical dysfunction associated with poor outcomes in adult patients, but its value in pediatric patients remains incomplete. Here, we assessed... -
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- Hemorrhagic Moyamoya Disease : A Recent Update
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Fujimura M, Tominaga T
- KMID: 2441557
- J Korean Neurosurg Soc.
- 2019 Mar;62(2):136-143.
- doi: 10.3340/jkns.2018.0101
Moyamoya disease (MMD) is a progressive cerebrovascular disease with unknown etiology, characterized by bilateral stenoocclusive changes at the terminal portion of the internal carotid artery and an abnormal vascular network... -
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- Persistent Malfunction of Glymphatic and Meningeal Lymphatic Drainage in a Mouse Model of Subarachnoid Hemorrhage
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Pu T, Zou W, Feng W, Zhang Y, Wang L, Wang H, Xiao M
- KMID: 2439010
- Exp Neurobiol.
- 2019 Feb;28(1):104-118.
- doi: 10.5607/en.2019.28.1.104
Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event that often is followed by permanent brain impairments. It is necessary to explore the pathogenesis of secondary pathological damages in order to... -
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- Restorative Mechanism of Neural Progenitor Cells Overexpressing Arginine Decarboxylase Genes Following Ischemic Injury
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Kim JY, Kim JY, Kim JH, Jung H, Lee WT, Lee JE
- KMID: 2439009
- Exp Neurobiol.
- 2019 Feb;28(1):85-103.
- doi: 10.5607/en.2019.28.1.85
Cell replacement therapy using neural progenitor cells (NPCs) following ischemic stroke is a promising potential therapeutic strategy, but lacks efficacy for human central nervous system (CNS) therapeutics. In a previous... -
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- Hyperglycemia aggravates decrease in alpha-synuclein expression in a middle cerebral artery occlusion model
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Kang JB, Kim DK, Park DJ, Shah MA, Kim MO, Jung EJ, Lee HS, Koh PO
- KMID: 2459295
- Lab Anim Res.
- 2018 Dec;34(4):195-202.
- doi: 10.5625/lar.2018.34.4.195
Hyperglycemia is one of the major risk factors for stroke. Hyperglycemia can lead to a more extensive infarct volume, aggravate neuronal damage after cerebral ischemia. α-Synuclein is especially abundant in... -
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- Ischemic Stroke in a Patient with Heterozygote Fabry's Disease
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Yang SW, Choi JC, Kim HW, Jeong JH, Hyun CL, Koh MJ
- KMID: 2435848
- J Korean Neurol Assoc.
- 2018 Nov;36(4):341-344.
- doi: 10.17340/jkna.2018.4.14
It is uncommon for Fabry's disease (FD) patient to present with an isolated ischemic stroke without other typical symptoms or signs of FD. A 48-year-old woman presented with recurrent limb... -
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- Neuroimaging Findings of First-Visit Headache Patients
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Kim BS, Kim SK, Kim JM, Moon HS, Park KY, Park JW, Sohn JH, Song TJ, Chu MK, Cha MJ, Kim BK, Cho SJ
- KMID: 2435838
- J Korean Neurol Assoc.
- 2018 Nov;36(4):294-301.
- doi: 10.17340/jkna.2018.4.4
BACKGROUND: Neuroimaging can play a crucial role in discovering potential abnormalities to cause secondary headache. There has been a progress in the fields of headache diagnosis and neuroimaging in the... -
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- The potential of earthworm and its components as a therapeutic agent for neuronal damage
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Moon BC, Kim JS
- KMID: 2435757
- J Biomed Transl Res.
- 2018 Sep;19(3):58-64.
- doi: 10.12729/jbtr.2018.19.3.058
Earthworms have been employed in traditional oriental medicine for the treatment of neurological disorders, as anticonvulsants, analgesics, and sedatives. In fact, earthworms are currently used as a medicinal agent in... -
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- Percutaneous Left Atrial Appendage Occlusion for the Prevention of Stroke in Patients with Atrial Fibrillation: Review and Critical Appraisal
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Schellinger PD, Tsivgoulis G, Steiner T, Köhrmann
- KMID: 2428764
- J Stroke.
- 2018 Sep;20(3):281-291.
- doi: 10.5853/jos.2018.02537
The authors review the current status of percutaneous left atrial appendage (LAA) occlusion therapy in patients with atrial fibrillation with the goal to prevent ischemic stroke and systemic embolism and... -
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