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Effects of Lamotrigine on Problem-Solving Abilities in Newly Diagnosed Pediatric Patients with Epilepsy

Lee SH, Kim SJ

BACKGROUND AND PURPOSE: This study aimed to determine the effects of lamotrigine (LTG) on language unction, including problem-solving abilities, in newly diagnosed pediatric epileptic patients. METHODS: This study included 112 newly...
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Analysis of factors involved in brain-death donor processing for face transplantation in Korea: How much time is available from brain death to transplantation?

Hong JW, Chung SW, Ahn SJ, Lee WJ, Lew DH, Kim YO

BACKGROUND: Face transplantation has naturally evolved from reconstructive procedures. However, few institutions perform face transplantations, because it is time-consuming and it is necessary to justify non-vital organ transplantation. We investigated...
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Prognostic Factors for Absence Epilepsy in Childhood

Kang SY, Koo CM, Kim SH, Kim HD, Lee JS, Kang HC

PURPOSE: Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary. We aimed to...
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Prognostic Factors for Absence Epilepsy in Childhood

Kang SY, Koo CM, Kim SH, Kim HD, Lee JS, Kang HC

PURPOSE: Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary. We aimed to...
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Predicting Symptomatic and Functional Improvements over 1 Year in Patients with First-Episode Psychosis Using Resting-State Electroencephalography

Renaldi R, Kim M, Lee TH, Kwak YB, Tanra AJ, Kwon JS

OBJECTIVE: Although early intervention from the beginning of a psychotic episode is essential for a better prognosis, biomarkers predictive of symptomatic and functional improvement in early psychotic disorders are lacking....
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Promising Neuroimaging Biomarkers in Depression

Lai CH

The neuroimaging has been applied in the study of pathophysiology in major depressive disorder (MDD). In this review article, several kinds of methodologies of neuroimaging would be discussed to summarize...
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Distinct Topographical Patterns of Spike-Wave Discharge in Transgenic and Pharmacologically Induced Absence Seizure Models

Lee S, Hwang E, Lee M, Choi JH

Absence seizures (AS) are generalized non-convulsive seizures characterized by a brief loss of consciousness and spike-and-wave discharges (SWD) in an electroencephalogram (EEG). A number of animal models have been developed...
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Assessment of phase-lag entropy, a new measure of electroencephalographic signals, for propofol-induced sedation

Jun MR, Yoo JH, Park SY, Na S, Kwon H, Nho JH, Kim SI

BACKGROUND: Phase-lag entropy (PLE) was recently described as a measurement of temporal pattern diversity in the phase relationship between two electroencephalographic signals from prefrontal and frontal montages. This study was...
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Management of post-cardiac arrest syndrome

Kang Y

Post-cardiac arrest syndrome is a complex and critical issue in resuscitated patients undergone cardiac arrest. Ischemic-reperfusion injury occurs in multiple organs due to the return of spontaneous circulation. Bundle of...
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Frontal Alpha Asymmetry Correlates with Suicidal Behavior in Major Depressive Disorder

Park Y, Jung W, Kim S, Jeon H, Lee SH

OBJECTIVE: Based on the constant associations made between major depressive disorder (MDD) and alpha asymmetry, and MDD and suicide, this study aimed to examine the relationship between frontal alpha asymmetry...
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Severe Temporal Hyper-Activated States Caused by Noise in Tinnitus and Hyperacusis with Normal Hearing

Bae EB, Lee JH

Lots of neuroimaging and animal studies have revealed that tinnitus and hyperacusis share the same patterns in the bottom up central auditory process. The aim was to identify the abnormal...
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Clinical Significance of Asymmetric Minimum Intensity Projection Images of Brain Magnetic Resonance Imaging in Children

Kim HS, Kim SJ, Kong YH

BACKGROUND AND PURPOSE: The susceptibility-weighted imaging form of brain MRI using minimum intensity projection (mIP) is useful for assessing traumatic brain injuries because it readily reveals deoxyhemoglobin or paramagnetic compounds....
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Reconsideration of Vigabatrin Effect in Infantile Spasms Treatment

Yoon DH, Moon JU, Lee JY, Lee IG

PURPOSE: To investigate the effect of vigabatrin (VGB) as a therapeutic agent for patients with infantile spasms (IS), compare risk factors for treatment response, and review safety of VGB by...
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Treatment Response to Acquired Aphasia with Seizures and Prognosis through Electroencephalogram on Cognitive Function

Koo CM, Kim SH, Kim HD, Lee JS, Kang HC

PURPOSE: Acquired epileptic aphasia (AEA) accompanied by electroencephalogram (EEG) abnormality is a rare disease; therefore, there are few studies investigating the prognostic factors and treatment efficacy. We aimed to determine...
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Clinical Features and Treatment Efficacy in CDKL5 Mutation-Related Epileptic Encephalopathy in the Infant

Koo CM, Kim SH, Kim HD, Lee JS, Choi JR, Lee ST, Kang HC

PURPOSE: Mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with epileptic encephalopathy and severe cognitive impairment. We aim to characterize the association between this gene and treatment efficacy. METHODS:...
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Electroencephalographic Changes Induced by a Neurofeedback Training : A Preliminary Study in Primary Insomniac Patients

Lee JH, Shin HB, Kim JW, Suh HS, Lee YJ

OBJECTIVES: Insomnia is one of the most prevalent sleep disorders. Recent studies suggest that cognitive and physical arousal play an important role in the generation of primary insomnia. Studies have...
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Generalized periodic discharges with triphasic morphology

Hartshorn , Foreman B

Generalized periodic discharges (GPDs) with triphasic morphology are an electroencephalographic (EEG) pattern traditionally associated with encephalopathy and coma, although they have been observed in a wide array of neurological disorders....
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Reconsideration of Vigabatrin Effect in Infantile Spasms Treatment

Yoon DH, Moon JU, Lee JY, Lee IG

PURPOSE: To investigate the effect of vigabatrin (VGB) as a therapeutic agent for patients with infantile spasms (IS), compare risk factors for treatment response, and review safety of VGB by...
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Treatment Response to Acquired Aphasia with Seizures and Prognosis through Electroencephalogram on Cognitive Function

Koo CM, Kim SH, Kim HD, Lee JS, Kang HC

PURPOSE: Acquired epileptic aphasia (AEA) accompanied by electroencephalogram (EEG) abnormality is a rare disease; therefore, there are few studies investigating the prognostic factors and treatment efficacy. We aimed to determine...
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Clinical Features and Treatment Efficacy in CDKL5 Mutation-Related Epileptic Encephalopathy in the Infant

Koo CM, Kim SH, Kim HD, Lee JS, Choi JR, Lee ST, Kang HC

PURPOSE: Mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with epileptic encephalopathy and severe cognitive impairment. We aim to characterize the association between this gene and treatment efficacy. METHODS:...
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