Korean J Dermatol.
2003 Dec;41(12):1644-1649.
Two Cases of Generalized Pustular Psoriasis Improved with Combination Treatment of Mycophenolate Mofetil
- Affiliations
-
- 1Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. nagy@knu.ac.kr
Abstract
- Mycophenolate mofetil(MMF) is a new immunosuppressant which non-competitively and reversibly blocks the de novo synthesis of guanine nucleotides required for DNA and RNA synthesis during lymphocyte proliferation. So MMF selectively inhibits lymphocyte proliferation and it has less side-effects than other immunosuppressants. We described 2 cases of generalized pustular psoriasis improved with MMF. We administered MMF combined with cyclosporin in case 1 and acitretin in case 2. Both patients markedly improved with MMF administration 3 days after and had no severe side-effects. Thus the authors thought that MMF appears to be an effective therapeutic alternative in the treatment of generalized pustular psoriasis.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Two Cases of Combined Geographic Tongue and Fissured Tongue in Generalized Pustular Psoriasis
- A Case of Generalized Pustular Psoriasis Improved with Isotretinoin
- Two Cases of Generalized Pustular Psoriasis in Brother and Sister
- A Case of Annular Pustular Psoriasis Showing Features of Subcorneal Pustular Dermatosis
- A Case of Recurrent Generalized Pustular Psoriasis Treated with a Combination of Infliximab with Methotrexate and Retinoid
