Clin Endosc.  2015 Jul;48(4):336-339. 10.5946/ce.2015.48.4.336.

A Patient with Duodenal Mucinous Adenocarcinoma Presenting as a Laterally Spreading Tumor

• Chae MJ
• Baek IH
• Oh YM
• Lim JU
• Jeon JW
• Shin HP
• Joo KR
• Lee JI

• KMID: 1964279
• DOI: http://doi.org/10.5946/ce.2015.48.4.336

Abstract

Primary duodenal carcinoma is rare. Duodenal mucinous adenocarcinoma (DMA) is even rarer, and its associated manifestations and typical endoscopic or imaging findings are not well characterized. Herein, we report a case of primary DMA in an asymptomatic 58-year-old man who visited our hospital for a regular health screening. Upper endoscopy revealed an approximately 4-cm lesion in the second portion of the duodenum, but the mass was not visualized on computed tomography. Biopsies revealed a tubular adenoma that was subsequently resected. Frozen biopsies demonstrated DMA with a background of low-grade tubular adenoma for which we performed Roux-en-Y duodenojejunostomy and jejunojejunostomy. To our knowledge, this is the first report of a patient with DMA in Korea.

Keyword

Adenocarcinoma; Mucinous; Duodenal neoplasms; Adenoma

MeSH Terms

Adenocarcinoma
Adenocarcinoma, Mucinous*
Adenoma
Biopsy
Duodenal Neoplasms
Duodenum
Endoscopy
Humans
Korea
Mass Screening
Middle Aged

Figure

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  Fig. 1 Esophagogastroduodenoscopy. (A) A laterally spreading polyp with an irregular surface is visible in the second portion of the duodenum. (B) Follow-up endoscopy after 3 months, showing no evidence of recurrence or abnormal findings at the anastomosis within the duodenum.

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  Fig. 2 Duodenal biopsy histology. These show malignant cells floating in large pools of mucin (A, H&E stain, ×40; B, H&E stain, ×100).

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