Korean J Anesthesiol.  1983 Dec;16(4):320-323.

The Clinical Investigation of Pre- and Post-Operative Liver Function after Halothane Anesthesia in the Electric Burn Patients

• Cho YS
• Sung SO
• Park CN
• Kwon CJ

Abstract

After the clinical introduction of halothane, the problem of hepatotoxicity and mechanism has major implications for the practice of anesthesiology. This study was undertaken to investigate the liver function change after halothane anesthesia in 22 cases of electric burn patient. In this study, all cases had a great elevation of SGOT and SGPT levels, and previous experience of inhalation anesthesia, jaundice and who had not been transfused during this study. The following results were obtained: 1) Elevation of the SGOT and SGPT in electric burn patients may be influenced by damage of skeletal muscle and transaminase released into systemic circulation. 2) In the electric burn patients, elevation of the SGOT and SGPT does not enhance the susceptibility of the liver to injury by halothane.

MeSH Terms

Alanine Transaminase
Anesthesia*
Anesthesia, Inhalation
Anesthesiology
Aspartate Aminotransferases
Burns, Electric*
Halothane*
Humans
Jaundice
Liver*
Muscle, Skeletal
Alanine Transaminase
Aspartate Aminotransferases
Halothane