Korean J Thorac Cardiovasc Surg.  1999 Jun;32(6):518-524.

Modified Ultrafiltration in Pediatric Open Heart Surgery

• Lee JR
• Lim HG
• Kim YJ
• Rho JR
• Suh KP

Abstract

BACKGROUND: This study has proven the effect of modified ultrafiltration(MUF) performed after the cessation of cardiopulmonary bypass in pediatric patients who underwent open heart surgery. MATERIAL AND METHOD: From Jan. to Dec. 1997, modified ultrafiltration was performed after cardiopulmonary bypass in 50 infants with cyanotic heart disease and the results were compared to the control group of 50 patients with cyanotic heart disease in whom modified ultrafiltration was not used. Changes of hematocrit, central venous pressure, systolic and diastolic pressure, heart rate and body weight were compared. RESULT: Age and body weight were not different(p=0.38, p=0.46). Disease categories were similar. Average filtering volume was 60.0+/-29.2cc/kg for 7.0+/-2.4minutes of filtration. Mean hematocrit after filtration(MUF=36.1%, control=26.4%, p=0.001) was higher in the MUF group. Systolic (p=0.0001) and diastolic blood pressure(p=0.0001) were observed to increase more and the central venous pressure(p=0.02) and the heart rate(p=0.02) were lower after filtration in the MUF group.
CONCLUSION
This study demonstrated that modified ultrafiltration after cardiopulmonary bypass was a technically feasible option to improve the post-surgical course through the effective hemoconcentration, hemodynamic improvements, and body water control.

Keyword

Ultrafiltration; Cardiopulmonary bypass; Heart surgery, Pediatrics

MeSH Terms

Blood Pressure
Body Water
Body Weight
Cardiopulmonary Bypass
Central Venous Pressure
Filtration
Heart Diseases
Heart Rate
Heart*
Hematocrit
Hemodynamics
Humans
Infant
Thoracic Surgery*
Ultrafiltration*