J Korean Neurotraumatol Soc.  2008 Jun;4(1):14-18. 10.13004/jknts.2008.4.1.14.

Analysis of Prognostic Factors for Chronic Subdural Hematoma

Affiliations
  • 1Department of Neurosurgery, College of Medicine, Chung-Ang University, Seoul, Korea. nspsw@cau.ac.kr

Abstract


OBJECTIVE
Chronic subdural hematoma (CSDH) is a relatively common disease with a simple treatment strategy. However, the prognosis for CSDH patient is not always easily determined. The aim of this study was to investigate the prognostic factors for patients with CSDH.
METHODS
Forty-six patients who were treated with burrhole trephination surgery for CSDH were retrospectively analyzed. The possible prognostic factors were age, sex, the size of the hematoma, pre-operative midline shifting, density and the location of the hematoma, pre-operative Glasgow Coma Scale (GCS), medical histories, post-operative brain expansion, and post-operative pneumocephalus. Post-operative clinical outcomes were evaluated by modified Rankin Scale (good outcome: mRS 0-1, poor outcome: mRS 2-5).
RESULTS
Among 46 patients, 33 patients (72%) were in the good outcome group while 13 (28%) patients demonstrated a poor outcome. Among variable factors, being older than 65 years, a poor pre-operative GCS (6-12) and a history of diabetes were significantly related to a poor clinical outcome statistically. As a result of logistic regression analysis for these factors, being older than 65 years and a pre-operative GCS under 12 were revealed as independent prognostic factors for CSDH.
CONCLUSION
Being older than 65 years and a pre-operative GCS under 12 were independent, significant prognostic factors for CSDH. The presence of diabetes was also statistically related with a poor prognosis without a high-risk value. These results could be helpful to predict the prognosis for CSDH after burrhole trephination.

Keyword

Chronic subdural hematoma; Burrhole trephination; Prognostic factor

MeSH Terms

Brain
Glasgow Coma Scale
Hematoma
Hematoma, Subdural, Chronic
Humans
Logistic Models
Pneumocephalus
Prognosis
Retrospective Studies

Cited by  1 articles

Clinical Characteristics of Bilateral versus Unilateral Chronic Subdural Hematoma
Jungjun Lee, Jae Hyo Park
Korean J Neurotrauma. 2014;10(2):49-54.    doi: 10.13004/kjnt.2014.10.2.49.


Reference

1. Drapkin AJ. Chronic subdural hematoma: pathophysiological basis for treatment. Br J Neurosurg. 1991; 5:467–473.
Article
2. Echlin FA, Sordillo SV, Garvey TQ Jr. Acute, subacute, and chronic subdural hematoma. J Am Med Assoc. 1956; 161:1345–1350.
Article
3. Fihn SD, McDonell M, Martin D, Henikoff J, Vermes D, Kent D, et al. Warfarin Optimized Outpatient Follow-up Study Group. Risk factors for complications of chronic anticoagulation. A multicenter study. Ann Intern Med. 1993; 118:511–520.
Article
4. Gardner WJ. Traumatic subdural hematoma with particular reference to the latent interval. Arch Neurol Psychiat. 1932; 27:847–858.
Article
5. Goldberg RJ, Gore JM, Gerwitz JH. The impact of age on the incidence and prognosis of initial acute myoardial infarction: the hertzer heart attack study. Am Heart J. 1989; 117:543–549.
6. Hammermeister KE, Sethi GK, Henderson WG, Oprian C, Kim T, Rahimtoola S. Veterans Affairs Cooperative Study on Valvular Heart Disease. A comparison of outcomes in men 11 years after heart-valve replacement with a mechanical valve or bioprosthesis. N Engl J Med. 1993; 328:1289–1296.
Article
7. Hancock DO. Cerebral collapse associated with chronic subdural hematoma in adults: a comparison of two methods of treatment. Lancet. 1965; 1:633–634.
8. Yamamoto H, Hirashima Y, Hamada H, Hayashi N, Origasa H, Endo S. Independent predictors of recurrence of chronic subdural hematoma: results of multivariate analysis performed using a logistic regression model. J Neurosurg. 2003; 98:1217–1221.
Article
9. Jamieson KG, Yelland JD. Surgically treated traumatic subdural hematomas. J Neurosurg. 1972; 37:137–149.
Article
10. Kannel WB, Abbott RD, Savage DD, McNamara PM. Epidemiologic features of chronic atrial fibrillation: the Framingham study. N Engl J Med. 1982; 306:1018–1022.
11. Mori K, Maeda M. Surgical treatment of chronic subdural hematoma in 500 consecutive cases: clinical characteristics, surgical outcome, complications, and recurrence rate. Neurol Med Chir (Tokyo). 2001; 41:371–381.
Article
12. Kotwica Z, Brzeziński J. Chronic subdural haematoma treated by burr holes and closed system drainage: personal experience in 131 patients. Br J Neurosurg. 1991; 5:461–465.
Article
13. Markwalder TM. Chronic subdural hematomas: a review. J Neurosurg. 1981; 54:637–645.
Article
14. Mellergard P, Wiston O. Operations and re-operations for chronic subdural haematomas during a 25-year period in a well defined population. Acta Neurochir (Wien). 1996; 138:708–713.
15. Merlicco G, Pierangeli E, di Padova PL. Chronic subdural hematomas in adults: prognostic factors. Analysis of 70 cases. Neurosurg Rev. 1995; 18:247–251.
Article
16. Nagata K, Asano T, Basugi N, Takara K. Studies on the operative factors affecting the reduction of chronic subdural hematoma with special reference to the residual air in the hematoma cavity. No Shinkei Geka. 1989; 17:15–20.
17. Obana WG, Pitts LH. Management of head injury. Extracerebral lesions. Neurosurg Clin N Am. 1991; 2:351–372.
18. Rankin J. Cerebral vascular accidents in patients over the age of 60. II. Prognosis. Scott Med J. 1957; 2:200–215.
Article
19. Richter HP, Klein HJ, Schäfer M. Chronic subdural haematomas treated by enlarged burr-hole craniotomy and closed system drainage. Retrospective study of 120 patients. Acta Neurochir (Wien). 1984; 71:179–188.
Article
20. Robinson RG. Chronic subdural haematoma: surgical management in 133 patients. J Neurosurg. 1984; 61:263–268.
21. Rozzelle CJ, Wofford JL, Branch CL. Predictors of hospital mortality in older patients with subdural hematoma. J Am Geriatr Soc. 1995; 43:240–244.
Article
22. Sambasivan M. An overview of chronic subdural haematoma: experience with 2300 cases. Surg Neurol. 1997; 47:418–422.
23. Scotti G, Terbrugge K, Melançon D, Bélanger G. Evaluation of the age of subdural haematomas by computed tomography. J Neurosurg. 1977; 47:311–315.
24. Tabaddor K, Shulman K. Definitive treatment of chronic subdural hematoma by twist-drill craniotomy and closed-system drainage. J Neurosurg. 1977; 46:220–226.
25. van Havenbergh T, van Calenbergh F, Goffin J, Plets C. Outcome of chronic subdural haematoma: analysis of prognostic factors. Br J Neurosurg. 1996; 10:35–39.
26. Weisse A, Berney J. Chronic subdural haematomas. Results of a closed drainage method in adults. Acta Neurochir (Wien). 1994; 127:37–40.
Article
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