Anesth Pain Med.  2013 Jul;8(3):171-174.

A suspicious case of malignant hyperthermia during general anesthesia with desflurane: A case report

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea. ishmael@freechal.com

Abstract

Malignant hyperthermia (MH) is an inherited disorder of skeletal muscle manifested as a life threatening hypermetabolic crisis in susceptible individuals following exposure to commonly used inhaled anesthetics and depolarizing muscle relaxants. We experienced a suspicious case of MH in 34-year-old male during transfemoral cerebral angiography embolization under general anesthesia with desflurane. The episode emerged 15 minutes after induction of general anesthesia using propofol, rocuronium, remifentanil, desflurane. Desflurane is a recently developed inhaled anesthetics and there has been no case report of MH related with it in Korea. When we suspected episode, vigorous treatment was carried out, symptoms were resolved without dantrolene administration.

Keyword

Dantrolene; Desflurane; Fresh gas flow; Malignant hyperthermia

MeSH Terms

Androstanols
Anesthesia, General
Anesthetics
Cerebral Angiography
Dantrolene
Humans
Isoflurane
Korea
Male
Malignant Hyperthermia
Muscle, Skeletal
Neuromuscular Depolarizing Agents
Piperidines
Propofol
Androstanols
Anesthetics
Dantrolene
Isoflurane
Neuromuscular Depolarizing Agents
Piperidines
Propofol
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