Korean J Anesthesiol.  1989 Jun;22(3):465-469. 10.4097/kjae.1989.22.3.465.

Malignant Hyperthermia during General Anesthesia - A case report

• Lee KC
• Lim SH
• Yoon SM

• KMID: 1751766
• DOI: http://doi.org/10.4097/kjae.1989.22.3.465

Abstract

Malignant hyperthermia is a potentially fatal hypermetabolic syndrome characterized by hyperpyr-exia and skeletal muscle rigidity. It can be induced by all of the currently used inhalation anesthetics or by injection of succinylcholine. This case is presented of a 32 year old healthy male patient in whom a orthopedic operation was performed under O2-N2O-enflurane anesthesia with induction by pentothal sodium and succinylcholine. One hour after induction, tachycardia developed and was followed by unstable blood pressure, hyperpyrexia, arrhythmia and muscle rigidity. Anesthesia was terminated and vigorous emergency treatment was attempted. But the patient died about 4 hours after induction of anesthesia. The etiologic factors, clinical feature, treatment and prevention of malignant hyperthermia are discussed.

Keyword

Malignant hyperthermia; Succinylcholine; Hyperpyrexia

MeSH Terms

Adult
Anesthesia
Anesthesia, General*
Anesthetics, Inhalation
Arrhythmias, Cardiac
Blood Pressure
Emergency Treatment
Humans
Male
Malignant Hyperthermia*
Muscle Rigidity
Muscle, Skeletal
Orthopedics
Sodium
Succinylcholine
Tachycardia
Thiopental
Anesthetics, Inhalation
Sodium
Succinylcholine
Thiopental