J Korean Med Sci.  2004 Jun;19(3):458-461. 10.3346/jkms.2004.19.3.458.

Intrapulmonary Cystic Lymphangioma in a 2-month-old Infant

• Lee CH
• Kim YD
• Kim KI
• Lim YT
• Lee KM
• Choi KU
• Lee JS
• Sol MY

• KMID: 1786828
• DOI: http://doi.org/10.3346/jkms.2004.19.3.458

Abstract

Lymphangioma is an abnormal collection of lymphatics that are developmentally isolated from the normal lymphatic system. Lymphangioma rarely presents as a solitary pulmonary lesion. We report a rare case of intrapulmonary cystic lymphangioma involving the upper lobe of the right lung, which presented with dyspnea in a 2-month-old infant. High-resolution computed tomography (HRCT) of the chest demonstrated a well-circumscribed, multiseptate, cystic lesion in the upper lobe of the right lung, mimicking the feature of type I congenital cystic adenomatoid malformation. The tumor was removed by bilobectomy of the upper and middle lobes of the right lung, and its pathologic examination confirmed the diagnosis of an intrapulmonary cystic lymphangioma.

Keyword

Lung; Lymphangioma, Cystic; Infant

MeSH Terms

Female
Human
Immunohistochemistry
Infant
Lung/pathology
Lung Neoplasms/*diagnosis/pathology
Lymphangioma, Cystic/*diagnosis/pathology
Tomography, X-Ray Computed

Figure

• 

  Fig. 1 High-resolution computed tomography of the chest depicts a well-circumscribed, multiseptate, air-filled cystic lesion in the upper lobe of the right lung.

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  Fig. 2 1:1 scaned photograph shows a large intrapulmonary cystic tumor (Ly), causing emphysematous change (Em) in surrounding pulmonary parenchyma (H&E, ×1).

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  Fig. 3 The cystic walls (in the right top) of the tumor are supported by loose fibrous tissue and adjoin to the emphysematous lung tissue (in the left) (H&E, ×20).

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  Fig. 4 Immunohistochemical staining for factor VIII-related antigen shows weak positive reactions in the lining cells of the cystic walls (Streptavidin-biotin, ×100).

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