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Hypothalamic AMP-Activated Protein Kinase as a Whole-Body Energy Sensor and Regulator

Min SH, Song DK, Lee CH, Roh E, Kim MS

5´-Adenosine monophosphate (AMP)-activated protein kinase (AMPK), a cellular energy sensor, is an essential enzyme that helps cells maintain stable energy levels during metabolic stress. The hypothalamus is pivotal in regulating...
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Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning

Lee CH, Jo DJ, Oh JK, Hyun SJ, Park JH, Kim KH, Bae JS, Moon BJ, Lee CK, Shin MH, Jang HJ, Han MS, Kim CH, Chung CK, Moon SM, for the Korean Spinal Deformity Society

Objective: Although adult spinal deformity (ASD) surgery aims to restore and maintain alignment, proximal junctional kyphosis (PJK) may occur. While existing scoring systems predict PJK, they predominantly offer a generalized...
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Fibroepithelial Polyp Arising From the Nasal Septum: A Case Report and a Literature Review

Jin W, Lee CH, Lee TH, Kim SW

Fibroepithelial polyp (FEP) is a benign tumor of mesodermal origin, which is mostly found on the skin. FEPs in the upper respiratory system are reported mostly originating from the oropharynx...
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An Intravertebral Pseudoaneurysm Formed after Infective Spondylitis

Kim S, Kang CK, Park H, Kim YR, Kim JH, Lee CH, Chung CK, Kim CH

The surgical treatment of spondylitis involves potential risks, especially when dealing with infected tissues that may be fragile and susceptible to injury from surgical trauma and inflammation. In cases where...
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The Influence of Spondylolisthesis Reduction on the Adjacent Lumbar Segment

Park TH, Choi Y, Kim TS, Kim JH, Lee CH, Kim S, Kim YR, Ko YS, Yuh WT, Rhee JM, Kim KT, Chung CK, Kim CH

Objective: Mild to moderate stenosis at the adjacent level sometimes co-occurs with lumbar spondylolisthesis, but whether to include the adjacent level during surgery for the index level is a matter...
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Latanoprostene Bunod 0.024% w/v Treatment of Open-anlge Glaucoma: Short-term Effects, Safety, and Changes in Ocular Blood

Kim HW, Lee CE, Seo S, Lee KW, Lee CH

Purpose: To study the short-term intraocular pressure (IOP)-lowering effect and optic nerve head (ONH) blood flow improvement after switching from latanoprost 0.005% w/v to latanoprostene bunod 0.024% w/v. Methods: This prospective...
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A Rare Case of Hypertrophic Pachymeningitis after Surgery for Chronic Subdural Hemorrhage: A Case Report

Lee YM, Lee CH, Kim CH, Kim YH, Sung SK, Son DW, Lee SW, Song GS

Hypertrophic pachymeningitis (HP) is a rare type of inflammatory fibrosis characterized by diffuse thickening of the dura mater, which may cause a compressive effect or vascular compromise. Progressively worsening headache...
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Treatment of phlegmonous esophagitis in various patients: a case series

Lee HS, Lee CH, Jeon YH

Acute phlegmonous esophagitis (APE) is a rare and fatal disease. Phlegmonous infection involves the submucosal layer and muscularis propria but not the mucosal layer. Because surgery is not the first...
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Intravesical bacillus Calmette–Guérin-induced myopathy presenting as rhabdomyolysis: a case report

Lee CH, Choi BJ, Kim JH, Yang TW, Kim GJ, Shin HY, Kim SH, Kim SW

Intravesical bacillus Calmette–Guérin (BCG) instillation is an adjuvant treatment for non–muscle-invasive urinary bladder cancer. Although most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have...
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The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study

Kim JY, Jung JW, Kang MJ, Kim DK, Choi H, Cho YJ, Jang SH, Lee CH, Oh YM, Park JS

Background/Aims: The overall incidence of pneumococcal pneumonia is declining. However, the change in the pathogenic distribution of community-acquired pneumonia (CAP) in chronic obstructive pulmonary disease (COPD) patients and the serotype...
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Pituitary Neuroendocrine Tumor: Is It Benign or Malignant?

Lee CH

The World Health Organization (WHO) updated the classification of pituitary tumors in 2022. The new classification presents detailed histological subtyping of a pituitary neuroendocrine tumor (PitNET) based on the tumor...
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Evaluation of the proximal contact and comparison of methods for measuring in normal dentition

Kim JE, Lee CH

Purpose The aim of this study was to evaluate the proximal contact with a dental floss compared to a celluloid strip and a metal strip in normal dental arch and investigate...
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Hypoalbuminemia and Albumin Replacement during Extracorporeal Membrane Oxygenation in Patients with Cardiogenic Shock

Jeon JB, Lee CH, Lim Y, Kim MC, Cho HJ, Kim DW, Lee KS, Jeong IS

Background: Extracorporeal membrane oxygenation (ECMO) has been widely used in patients with cardiorespiratory failure. The serum albumin level is an important prognostic marker in critically ill patients. We evaluated the...
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Effect of Hyaluronic Acid Injection for Dysphagia Due to Vocal Fold Paralysis after Influenza Infection – A Case Report

Kim YK, Lee CH, Lee M

A 74-year-old female patient was diagnosed with unilateral vocal fold paralysis without any brain lesions, but with a history of influenza infection 1 week ago. No significant manifestations were observed...
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Usefulness of Corticomedullary-Phase CT Urography in Patients with Suspected Acute Renal Colic Visiting the Emergency Department

Lee S, Park YS, Park B, Lee J, Choi JW, Kim KA, Lee CH

Purpose To evaluate the sensitivity of corticomedullary-phase imaging for detecting urinary stones in patients with renal colic who visited the emergency department. Materials and Methods This retrospective study included 253 patients with suspected...
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LKB1/STK11 Tumor Suppressor Reduces Angiogenesis by Directly Interacting with VEGFR2 in Tumorigenesis

Rho SB, Byun HJ, Kim BR, Lee CH

Cervical tumors represent a prevalent form of cancer affecting women worldwide; current treatment options involve surgery, radiotherapy, and chemotherapy. Angiogenesis, the process of new blood vessel formation, is a crucial...
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The Optimal Time between Embolization and Surgery for Hypervascular Spinal Metastatic Tumors : A Systematic Review and Meta-Analysis

Yuh WT, Han J, Lee CH, Kim CH, Kang HS, Chung CK

Objective : Preoperative transarterial embolization (TAE) of tumor feeders in hypervascular spine metastasis is known to reduce intraoperative estimated blood loss (EBL) during surgery. The effect of TAE varies for...
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Machine Learning-Based Proteomics Reveals Ferroptosis in COPD PatientDerived Airway Epithelial Cells Upon Smoking Exposure

Yoon JK, Park S, Lee KH, Jeong D, Woo J, Park J, Yi SM, Han D, Yoo CG, Kim S, Lee CH

Background: Proteomics and genomics studies have contributed to understanding the pathogenesis of chronic obstructive pulmonary disease (COPD), but previous studies have limitations. Here, using a machine learning (ML) algorithm, we...
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Animal models of inflammatory bowel disease: novel experiments for revealing pathogenesis of colitis, fibrosis, and colitis-associated colon cancer

Lee CH, Koh SJ, Radi ZA, Habtezion A

Inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis, is a lifelong disease that manifests with chronic intestinal inflammation, sequential fibrosis, and an increased risk of colitis-associated colon cancer...
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The solid predominant subtype as an independent risk factor for recurrence in patients with pathologic stage I lung adenocarcinoma

Lee CH, Jeon YH

Background: Increasingly many patients have been diagnosed with stage I adenocarcinoma due to the use of low-dose chest computed tomography for lung cancer screening. Therefore, this study aimed to analyze...
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