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HPV-18 E7 Interacts with Elk-1 Leading to Elevation of the Transcriptional Activity of Elk-1 in Cervical Cancer

Go SH, Rho SB, Yang DW, Kim BR, Lee CH, Lee SH

The human papillomavirus (HPV)-18 E7 (E7) oncoprotein is a major transforming protein that is thought to be involved in the development of cervical cancer. It is well-known that E7 stimulates...
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Prognostic value of the endothelial activation and stress index in patients with upper tract urothelial cancer undergoing radical nephroureterectomy

Gu JS, Ryu JW, Yu SH, Chung HS, Hwang JE, Bae WK, Ku JY, Lee CH, Ha HK, Jung SI, Hwang EC, Kwon DD

Purpose: The relationship with endothelial activation and stress index (EASIX), which represents the degree of endothelial dysfunction, is unwell known in upper tract urothelial carcinoma (UTUC). The present study aims...
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Surgical and Electrical Anatomy of the Inter-Nodal and Intra-Atrial Conduction System in the Heart

Seo JW, Kim JS, Cha MJ, Yoon JK, Kim MJ, Tsao HM, Lee CH, Oh S

An anatomical understanding of the atrial myocardium is crucial for surgeons and interventionists who treat atrial arrhythmias. We reviewed the anatomy of the inter-nodal and intra-atrial conduction systems. The anterior...
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Humulus japonicus attenuates LPS-and scopolamine-induced cognitive impairment in mice

Go J, Park HY, Lee DW, Maeng SY, Lee IB, Seo YJ, An JP, Oh WK, Lee CH, Kim KS

Background: Neuroinflammation plays an important role in cognitive decline and memory impairment in neurodegenerative disorders. Previously, we demonstrated that Humulus japonicus (HJ) has anti-inflammatory effects in rodent models of Alzheimer’s...
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Long-term Outcome of Fontan-Associated Protein-Losing Enteropathy: Treatment Modality and Predictive Factor of Mortality

Yoon JK, Kim GB, Song MK, Lee SY, Kim SH, Jang SI, Kim WH, Lee CH, Ahn KJ, Bae EJ

Background and Objectives: Protein-losing enteropathy (PLE) is a devastating complication after the Fontan operation. This study aimed to investigate the clinical characteristics, treatment response, and outcomes of Fontan-associated PLE. Methods: We...
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Efficacy and Safety of Subclinical Sensitization with Diphenylcyclopropenone in Children with Alopecia Areata: A Retrospective Study

Lee SH, Lee CH, Kang H, Lee WS

  • KMID: 2532296
  • Korean J Dermatol.
  • 2022 Jul;60(6):371-377.
Background: Contact immunotherapy with diphenylcyclopropenone is one of the first-line treatments for extensive alopecia areata, despite its adverse effects (AEs). Objective: This study aimed to investigate whether a modified contact immunotherapy...
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Effects of Sodium/Glucose Cotransporter 2 (SGLT2) Inhibitors on Cardiac Imaging Parameters: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Wee CF, Teo YH, Teo YN, Syn NL, See RM, Leong S, Yan Yip AS, Ong ZX, Lee CH, Chan MYY, Poh KK, Ong CC, Teo LL, Singh D, Tan BY, Yeo LL, Kong WK, Yeo TC, Wong RC, Chai P, Sia CH

Recent studies have shown that sodium/glucose cotransporter 2 (SGLT2) inhibitors might exert favourable changes on cardiac parameters as observed on cardiovascular imaging. We conducted a systematic review and meta-analysis to determine...
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Hypertrophic Pachymeningitis and Interstitial Lung Disease in IgG4-Related Disease

Yim SH, Yoon JS, Lee CH, Kim J

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The Association Between Bacille Calmette-Guérin Vaccination and Nontuberculous Mycobacterial Pulmonary Disease

Kwak N, Hwang HW, Kim HJ, Lee HW, Yim JJ, Lee CH

This study aimed to investigate the association between Bacille Calmette-Guérin (BCG) vaccination and nontuberculous mycobacterial pulmonary disease (NTM-PD). Patients in the prospective NTM-PD cohort were matched to healthy controls to...
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PRR16/Largen Induces Epithelial-Mesenchymal Transition through the Interaction with ABI2 Leading to the Activation of ABL1 Kinase

Kang GJ, Park JH, Kim HJ, Kim EJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Kim KS, Huy HP, Rahman M, Kim YH, Jang JY, Park MK, Lee H, Choi CI, Lee K, Han HK, Cho J, Rho SB, Lee CH

Advanced or metastatic breast cancer affects multiple organs and is a leading cause of cancer-related death. Cancer metastasis is associated with epithelial-mesenchymal metastasis (EMT). However, the specific signals that induce...
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Snail Promotes Cancer Cell Proliferation via Its Interaction with the BIRC3

Rho SB, Byun HJ, Kim BR, Lee CH

Snail is implicated in tumour growth and metastasis and is up-regulated in various human tumours. Although the role of Snails in epithelial-mesenchymal transition, which is particularly important in cancer metastasis,...
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The Efficacy of Three-Dimensional Sweeping Mode Extracorporeal Shockwave Treatment for Plantar Fasciitis

Lim JA, Lee CH, Park JH

Purpose: This was a pilot study to examine the clinical usefulness of the newly developed three-dimensional sweep mode extracorporeal shockwave treatment (ESWT) in patients with plantar fasciitis. Materials and Methods: Three-dimensional...
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Immunogenicity of COVID-19 Vaccination in Patients With End-Stage Renal Disease Undergoing Maintenance Hemodialysis: The Efficacy of a Mixand-Match Strategy

Park JS, Minn D, Hong S, Jeong S, Kim S, Lee CH, Kim B

Background: The objective of this study was to evaluate the immunogenicity of coronavirus disease 2019 (COVID-19) vaccination in patients with end-stage renal disease (ESRD) on hemodialysis. Methods: ESRD patients at the...
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Vortioxetine Treatment for Depression in Alzheimer’s Disease: A Randomized, Double-blind, Placebo-controlled Study

Jeong HW, Yoon KH, Lee CH, Moon YS, Kim DH

Objective: Vortioxetine, a new antidepressant, has been demonstrated to have effects on depression and cognitive function. This study aimed to investigate the anti-depressive efficacy of vortioxetine through a well-designed double-blind,...
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Impact of scanning strategy on the accuracy of complete-arch intraoral scans: a preliminary study on segmental scans and merge methods

Mai HY, Mai HN, Lee CH, Lee KB, Kim Sy, Lee JM, Lee KW, Lee DH

PURPOSE. This study investigated the accuracy of full-arch intraoral scans obtained by various scan strategies with the segmental scan and merge methods. MATERIALS AND METHODS. Seventy intraoral scans (seven scans per...
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A Case of Heart Transplantation for Fulminant Myocarditis After ChAdOx1 nCoV-19 Vaccination

Kim SH, Lee SY, Kim GY, Oh JS, Kim J, Chun KJ, Ju MH, Lee Ch, Song YJ, Na JY

Vaccines have become the mainstay of management against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019; COVID-19) in the absence of effective antiviral therapy. Various adverse effects...
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Effect of size and taper on the mechanical properties of profile and Hyflex CM Ni-Ti endodontic files

Lee H, Lee Ch, Lee Ib

The purpose of this study was to investigate the effect of size and taper on the mechanical properties of two Ni-Ti files. A controlled memory Ni-Ti file, Hyflex CM (Coltène-Whaledent,...
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Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan E, Kim HJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Do PA, Kim EJ, Kim KS, Huy HP, Rahman M, Jang JY, Rho SB, Lee H, Kang GJ, Park MK, Kim NH, Choi CI, Lee K, Han HK, Cho J, Lee AY, Lee CH

Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines...
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Long-Term Safety and Efficacy of Prolonged Dual Antiplatelet Therapy according to Baseline Anemia after Percutaneous Coronary Intervention

Kim HT, Lee JH, Nam JH, Lee CH, Son JW, Kim U, Park JS, Shin DG

Purpose: We aimed to evaluate the outcomes of prolonged dual antiplatelet therapy (DAPT) depending on baseline anemia after percutaneous coronary intervention (PCI). Materials and Methods: Among the 1470 study participants, 448...
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Effectiveness and Causes of Early Cessation of Intravenous Patient-Controlled Analgesia in Orthopedic Surgery

Lee BJ, Lee CH, Go J

Purpose: This study examined the frequency of early cessation of intravenous patient-controlled analgesia (IV-PCA) after orthopedic surgery, and the difference in frequency according to the surgical site and type to...
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