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Corrigendum to “Infection and Instability Increasing the Risk of Patella Baja and Pseudo-Patella Baja after Revision Total Knee Arthroplasty”

Song SJ, Park CH, Lee JW, Lee HW, Kim KI, Bae DK

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Meclofenamate Suppresses MUC5AC Mucin Gene Expression by Regulating the NF-kB Signaling Pathway in Human Pulmonary Mucoepidermoid NCI-H292 Cells

Ryu J, Kim Ki, Hossain R, Lee M, Hong JT, Lee HJ, Lee CJ

The current study aimed to reveal the potential effect of meclofenamate, a nonsteroidal anti-inflammatory drug, on the gene expression of airway MUC5AC mucin. Human pulmonary mucoepidermoid NCI-H292 cells were pretreated...
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Risk Stratification of Cardiovascular Disease according to Age Groups in New Prevention Guidelines: A Review

Kim Ki

Age is a strong risk factor for cardiovascular disease. Accordingly, most cardiovascular risk prediction models have included age as an independent risk factor. There is much evidence that effective management...
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Optimal target blood pressure in older patients with hypertension

Kim Ki

Hypertension is a common condition among older adults, and blood pressure (BP) control is effective for preventing cardiovascular morbidity and mortality even among the oldest-old adults. However, the optimal target...
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Pitavastatin Induces Apoptosis of Cutaneous Squamous Cell Carcinoma Cells through Geranylgeranyl PyrophosphateDependent c-Jun N-Terminal Kinase Activation

Kim KI, Kim SM, Lee YY, Lee Y, Kim CD, Yoon TJ

Background: Pitavastatin is a cholesterol-lowering drug and is widely used clinically. In addition to this effect, pitavastatin has shown the potential to induce apoptosis in cutaneous squamous cell carcinoma (SCC)...
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Health-Related Unmet Needs of Community-Dwelling Older Adults: A Nationwide Representative Descriptive Study in Korea

Huh Y, Son KY, Lee JE, Kim KI, Cho B, Won CW

Background: South Korea has no official geriatric specialties or subspecialties. Moreover, studies on the unmet needs related to geriatric health problems in older Korean adults are scarce. Therefore, we investigated...
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Infection and Instability Increasing the Risk of Patella Baja and Pseudo-Patella Baja after Revision Total Knee Arthroplasty

Song SJ, Park CH, Lee JW, Lee HW, Kim KI, Bae DK

Background: Patella baja with patellar tendon shortening due to traumatic or ischemic injury is a widely known complication after primary total knee arthroplasty (TKA). Pseudo-patella baja may arise from the...
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Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort

Lee JY, Bak JK, Kim M, Shin HG, Park KI, Lee SP, Lee HS, Lee JY, Kim Ki, Kang SH, Lee JH, Jang SY, Lee JH, Kim KH, Cho JY, Park JH, Park SK, Lee HY

Background/Aims: This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. Methods: The Korean Hypertension Cohort (KHC) enrolled 11,043 patients...
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Outcomes of Urgent Interhospital Transportation for Extracorporeal Membrane Oxygenation Patients

Yang JT, Kim HS, Kim KI, Ko HH, Lim JH, Lee HK, Ra YJ

Background: Extracorporeal membrane oxygenation (ECMO) can be used in patients with refractory cardiogenic shock or respiratory failure. In South Korea, the need for transporting ECMO patients is increasing. Nonetheless, information...
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Betulin, an Anti-Inflammatory Triterpenoid Compound, Regulates MUC5AC Mucin Gene Expression through NF-kB Signaling in Human Airway Epithelial Cells

Hossain R, Kim Ki, Jin F, Lee HJ, Lee CJ

Betulin is a triterpenoid natural product contained in several medicinal plants including Betulae Cortex. These medicinal plants have been used for controlling diverse inflammatory diseases in folk medicine and betulin...
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Blood Pressure Target in Type 2 Diabetes Mellitus

Kim HJ, Kim Ki, on Behalf of the Policy Committee of Korean Society of Hypertension

The prevalence of diabetes mellitus continues to increase worldwide, and it is a well-established cardiovascular risk factor. Hypertension is also an important cardiovascular risk factor to be controlled and is...
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Involvement of IKK/IkBα/NF-kB p65 Signaling into the Regulative Effect of Engeletin on MUC5AC Mucin Gene Expression in Human Airway Epithelial Cells

Hossain R, Kim Ki, Li X, Lee HJ, Lee CJ

In this study, we examined whether engeletin exerts an effect on the gene expression of MUC5AC mucin, in human pulmonary epithelial NCI-H292 cells. The cells were pretreated with engeletin for...
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Optimal blood pressure target in the elderly: rationale and design of the HOW to Optimize eLDerly systolic Blood Pressure (HOWOLD-BP) trial

Lee DH, Lee JH, Kim SY, Lee HY, Choi JY, Hong Y, Park SK, Ryu DR, Yang DH, Hwang SJ, Choi JH, Kim KH, Lee SH, Joo SJ, Park JH, Kim SH, Kim HL, Kim Ki, Cho MC

Background/Aims: The optimal systolic blood pressure (SBP) goal for elderly patients with hypertension, especially to reduce cardiovascular disease (CVD) incidence and improve outcome, is unclear. This study aimed to evaluate...
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Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension

Choi JH, Cho YJ, Kim HJ, Ko SH, Chon S, Kang JH, Kim KK, Kim EM, Kim HJ, Song KH, Nam GE, Kim KI, Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO), Committee of Clinical Practice Guidelines and Committee of Food and Nutrition, Korean Diabetes Association (KDA), Policy Committee of Korean Society of Hypertension (KSH), Policy Development Committee of National Academy of Medicine of Korea (NAMOK)

Carbohydrate-restricted diets and intermittent fasting (IF) have been rapidly gaining interest among the general population and patients with cardiometabolic disease, such as overweight or obesity, diabetes, and hypertension. However, there...
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Inhibitory Effect of Mitoxantrone on Collagen Synthesis in Dermal Fibroblasts

Kim KI, Kwon CI, Lee JH, Kim CD, Yoon TJ

Background: Fibroblasts produce collagen molecules that support the structure of the skin. The decrease and hypersynthesis of collagen causes skin problems such as skin atrophy, wrinkles and scars. Objective: The purpose of...
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Elevated On-Treatment Diastolic Blood Pressure and Cardiovascular Outcomes in the Presence of Achieved Systolic Blood Pressure Targets

Kim DH, Cho IJ, Kim W, Lee CJ, Kim HC, Shin JH, Kang SH, Jung MH, Kwon CH, Lee JH, Kim HL, Kim HM, Cho I, Kang DR, Lee HY, Chung WJ, Kim KI, Cho EJ, Sohn IS, Park S, Shin J, Ryu SK, Kang SM, Pyun WB, Cho MC, Kim JH, Lee JH, Ihm SH, Sung KC

Background and Objectives: This study aimed to investigate the association between cardiovascular events and 2 different levels of elevated on-treatment diastolic blood pressures (DBP) in the presence of achieved systolic...
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Factors Associated with Acute Hospitalizations and Mortality of Older Adults in Long-Term Care Facilities and Long-Term Care Hospitals: A Population-Based, Pubic-Insurance Big-Data Analysis

Lee S, Yoon NH, Choi JY, Kim KI, Kim H

Purpose: This study examined individual, institutional, and regional factors associated with 90-day acute hospitalizations and 1-year mortality among older people admitted to long-term care facilities (LTCFs) and long-term care hospitals...
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Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension

Choi JH, Cho YJ, Kim HJ, Ko SH, Chon S, Kang JH, Kim KK, Kim EM, Kim HJ, Song KH, Nam GE, Kim KI, Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO), Committee of Clinical Practice Guidelines and Committee of Food and Nutrition, Korean Diabetes Association (KDA), Policy Committee of Korean Society of Hypertension (KSH), Policy Development Committee of National Academy of Medicine of Korea (NAMOK)

Carbohydrate-restricted diets and intermittent fasting (IF) have been rapidly gaining interest among the general population and patients with cardiometabolic disease, such as overweight or obesity, diabetes, and hypertension. However, there...
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Assessing frailty using comprehensive geriatric assessment in older patients with hematologic malignancy

Choi JY, Kim Ki

The incidence of hematologic malignancy increases with age; thus, the number of older patients who require intensive chemotherapy is expected to increase with the aging population. In Korea, 61.8%, 59.3%,...
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Factors associated with anticholinergic burden among older patients in long-term care hospitals in Korea

Choi JY, Kim H, Jung Yi, Chun S, Yoo S, Lim JY, Ko JY, Park K, Kim Ki

Background/Aims: Drugs with anticholinergic properties (DAPs) are associated with adverse health outcomes in older patients. The objective of this study was to evaluate the factors that determine the prescribing of...
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