J Korean Med Sci.  2007 Jun;22(3):508-512. 10.3346/jkms.2007.22.3.508.

Cigarette Smoking and Risk of Lung Cancer in Korean Men: The Seoul Male Cancer Cohort Study

Affiliations
  • 1Department of Preventive Medicine, Cheju National University College of Medicine, Jeju, Korea.
  • 2Department of Preventive Medicine, Ulsan University College of Medicine, Seoul, Korea.
  • 3Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 4Department of Social Medicine, Hallym University College of Medicine, Seoul, Korea.
  • 5Institute of Radiation Effect & Epidemiology, Seoul National University College of Medicine, Seoul, Korea.
  • 6Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yeoungeun-dong, Jongro-gu, Seoul, Korea. yoahn@plaza.snu.ac.kr

Abstract

Lung cancer is the leading cause of cancer deaths in Korea. The aim of this study was to estimate lung cancer risk of cigarette smoking in Korean men by a 10-yr follow-up prospective cohort study using the primary databases. The number of subjects was 14,272 men, who had full information of smoking habits among participants in the Seoul Male Cancer Cohort Study (SMCC). Total 125,053 personyears were calculated by determining the number of days from the start of followup, January 1, 1993, until the date of lung cancer diagnosis, death from another cause, or the end of follow-up, December 31, 2002, followed by converting the number of days to years. The information of outcome was obtained by the database of Korea Central Cancer Registry, Seoul Regional Cancer Registry, and Korea Statistical Office. The relative risk (RR) and its 95% confidence interval (CI) values of smoking were calculated using Cox proportional hazards regression stratified on potential confounders. During the follow-up periods, 78 cases of lung cancer occurred. The cigarette smoking is the major risk factor and increases the 4.18-fold risk of lung cancer in Korean men. In order to control lung cancer, intervention of quitting smoking is needed.

Keyword

Lung Neoplasm; Cancer Incidence; Cigarette Smoking; Cohort Study

MeSH Terms

Adult
Cohort Studies
Follow-Up Studies
Humans
Korea
Lung Neoplasms/*diagnosis/*etiology
Male
Middle Aged
Proportional Hazards Models
Risk
Risk Factors
*Smoking
Treatment Outcome
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