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Acquired Resistance of MET-Amplified Non-small Cell Lung Cancer Cells to the MET Inhibitor Capmatinib

Kim S, Kim TM, Kim DW, Kim S, Kim M, Ahn YO, Keam B, Heo DS

PURPOSE: Amplified mesenchymal-epithelial transition factor, MET, is a receptor tyrosine kinase (RTK) that has been considered a druggable target in non-small cell lung cancer (NSCLC). Although multiple MET tyrosine kinase...
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Clinical Implications of VEGF, TGF-beta1, and IL-1beta in Patients with Advanced Non-small Cell Lung Cancer

Kim JW, Koh Y, Kim DW, Ahn YO, Kim TM, Han SW, Oh DY, Lee SH, Im SA, Kim TY, Heo DS, Bang YJ

  • KMID: 2167643
  • Cancer Res Treat.
  • 2013 Dec;45(4):325-333.
PURPOSE: Vascular endothelial growth factor (VEGF)-A, VEGF165b, interleukin (IL)-1beta, and transforming growth factor (TGF)-beta1 are known to influence tumor angiogenesis. Clinical implications of these cytokines need to be elucidated. MATERIALS AND...
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Cardiovascular Health Metrics and All-cause and Cardiovascular Disease Mortality Among Middle-aged Men in Korea: The Seoul Male Cohort Study

Kim JY, Ko YJ, Rhee CW, Park BJ, Kim DH, Bae JM, Shin MH, Lee MS, Li ZM, Ahn YO

  • KMID: 1711352
  • J Prev Med Public Health.
  • 2013 Nov;46(6):319-328.
OBJECTIVES: This study estimated the association of cardiovascular health behaviors with the risk of all-cause and cardiovascular disease (CVD) mortality in middle-aged men in Korea. METHODS: In total, 12 538 men...
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Perspectives of clinical epidemiology in Korea

Bae JM, Park BJ, Ahn YO

The establishment of clinical epidemiology has meant the improvement of the quality and quantity of clinical science because clinical epidemiology has contributed to the process of decision making across the...
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Pulmonary Tuberculosis and Lung Cancer Risk in Current Smokers: The Seoul Male Cancer Cohort Study

Bae JM, Li ZM, Shin MH, Kim DH, Lee MS, Ahn YO

Authors evaluated pulmonary tuberculosis (PTB) history as a risk factor for lung cancer in current male smokers in a prospective, population-based cohort study. The subjects were the 7,009 males among...
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Lung Cancer Incidence by Smoking Status in Korean Men: 16-Years of Observations in the Seoul Male Cancer Cohort Study

Bae JM, Li ZM, Shin MH, Kim DH, Lee MS, Ahn YO

The relative risk (RR) of smoking and mortality of lung cancer in British doctors was previously reported to have increased throughout a 40-yr period. Here, we evaluated this RR based...
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Cancer Risk in Adult Residents near Nuclear Power Plants in Korea: A Cohort Study of 1992-2010

Ahn YO, Li ZM, The KREEC Study Group

This study evaluated cancer risk for adult residents near Nuclear Power Plants (NPPs) in Korea through a valid prospective cohort study during 1992-2010. The study cohort was composed of 11,367...
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Prevalence Rate and Associated Factors of Sarcopenic Obesity in Korean Elderly Population

Hwang B, Lim JY, Lee J, Choi NK, Ahn YO, Park BJ

This study was conducted to estimate the prevalence rates and to explore associated factors of sarcopenic obesity (SO) in 2,221 Koreans over 60 yr-of age from the Fourth Korea National...
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Completeness of Cancer Case Ascertainment in Korea Radiation Effect and Epidemiology Cohort Study

Song M, Cho IS, Li ZM, Ahn YO

The aim of this study was to evaluate whether the completeness of case ascertainment during the follow-up of a cohort differed between the exposed and the nonexposed groups in Korea...
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Low Cholesterol is Associated with Mortality from Cardiovascular Diseases: A Dynamic Cohort Study in Korean Adults

Bae JM, Yang YJ, Li ZM, Ahn YO

This study was conducted to evaluate the association of single serum total cholesterol (TC) measurement with cardiovascular diseases (CVD) deaths in Korean adults. The study subjects were taken from the...
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Impact of Individual and Combined Health Behaviors on All Causes of Premature Mortality Among Middle Aged Men in Korea: The Seoul Male Cohort Study

Rhee CW, Kim JY, Park BJ, Li ZM, Ahn YO

OBJECTIVES: The aim of this study was to evaluate and quantify the risk of both individual and combined health behaviors on premature mortality in middle aged men in Korea. METHODS: In...
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Establishment of Korean Dietary Guidelines for Cancer Prevention

Lee SY, Shin MH, Sung MK, Paik HY, Park YK, Kim J, Sohn JW, Kim WG, Jung HJ, Ahn YO

  • KMID: 2305104
  • Korean J Health Promot.
  • 2011 Sep;11(3):129-143.
BACKGROUND: As a leading cause of death in Korea, cancer is known to be related to lifestyle including diet. In 2007, the World Cancer Research Fund announced 10 evidence-based guidelines...
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Concepts and necessity of preventive medical services for the 21st century

Ahn YO

  • KMID: 2341700
  • J Korean Med Assoc.
  • 2011 Mar;54(3):246-249.
Not only disease patterns but also the contents and concepts of medical services are rapidly changing recent years. A quick look at the evolution of health care services shows that...
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Power Estimation and Follow-Up Period Evaluation in Korea Radiation Effect and Epidemiology Cohort Study

Cho IS, Song M, Choi Y, Li ZM, Ahn YO

OBJECTIVES: The objective of this study was to calculate sample size and power in an ongoing cohort, Korea radiation effect and epidemiology cohort (KREEC). METHOD: Sample size calculation was performed...
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Reliability of Covariates in Baseline Survey of a Cohort Study: Epidemiological Investigation on Cancer Risk Among Residents Who Reside Near the Nuclear Power Plants in Korea

Bae S, Park BY, Li ZM, Ahn YO

OBJECTIVES: We evaluated the reliability of the possible covariates of the baseline survey data collected for the Epidemiological Investigation on Cancer Risk Among Residents Who Reside Near the Nuclear Power...
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Nationwide Cancer Incidence in Korea, 2003-2005

Won YJ, Sung J, Jung KW, Kong HJ, Park S, Shin HR, Park EC, Ahn YO, Hwang IK, Lee DH, Choi JS, Kim WC, Lee TY, Yoo CI, Bae JM, Kim ON, Chung W, Kong IS, Lee DH, Lee JS

  • KMID: 2128573
  • Cancer Res Treat.
  • 2009 Sep;41(3):122-131.
PURPOSE: To estimate the current cancer burden in Korea, newly diagnosed cancer cases and cancer incidence rates were calculated for the years 2003~2005. MATERIALS AND METHODS: The cancer incidence cases...
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Ten Year Trend of Cancer Incidence in Seoul, Korea: 1993-2002

Shin MH, Oh HK, Ahn YO

OBJECTIVES: Effective cancer prevention and control measures can only be done when dependable data on the cancer incidence is available. The Seoul Cancer Registry (SCR) was founded to provide...
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Cancer Registration in Korea: The Present and Furtherance

Ahn YO

It was not until 1975 that cancer registration was initiated in Korea; voluntary registration of cancer patients of training hospitals throughout the country began under the auspices of the Korean...
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Cigarette Smoking and Risk of Lung Cancer in Korean Men: The Seoul Male Cancer Cohort Study

Bae JM, Lee MS, Shin MH, Kim DH, Li ZM, Ahn YO

Lung cancer is the leading cause of cancer deaths in Korea. The aim of this study was to estimate lung cancer risk of cigarette smoking in Korean men by a...
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Seasonal Variation of Food Intake in Food Frequency Questionnaire among Workers in a Nuclear Power Plant

Yang JJ, Park SK, Lim HS, Ko KP, Ahn Y, Ahn YO

OBJECTIVES: This study was conducted to investigate the systematic error, such as seasonal change or inadequate food items, in a food frequency questionnaire administered to workers in a Nuclear...
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