J Korean Med Sci.  2011 May;26(5):642-646. 10.3346/jkms.2011.26.5.642.

Prevalence and Risk Factor of Erosive Esophagitis Observed in Korean National Cancer Screening Program

• Kim BJ
• Cheon WS
• Oh HC
• Kim JW
• Park JD
• Kim JG

• KMID: 1777863
• DOI: http://doi.org/10.3346/jkms.2011.26.5.642

Abstract

Prevalence of erosive esophagitis (EE) has been increasing in Korea. The purpose of this study was to estimate prevalence of EE among low socioeconomic population in Korea and to investigate risk factors for EE. We reviewed the medical records of 7,278 subjects who were examined by upper endoscopy in the Korean National Cancer Screening Program at Chung-Ang University Yong-san Hospital from March 2003 to March 2008. The study population included subjects > or = 40 yr of age who were Medicaid recipients and beneficiaries in the National Health Insurance Corporation. Multivariate analysis was used to determine risk factors for EE. Prevalence of EE was 6.7% (486/7,278). According to the LA classification system, LA-A in 344 subjects, LA-B in 135 subjects, and LA-C and D in 7 subjects. In multivariate analysis, age > or = 60 yr, male sex, BMI > or = 25, current smoking, alcohol consumption, fasting glucose level > or = 126 mg/dL, and endoscopic hiatal hernia were significant risk factors for EE. The prevalence of EE in low socioeconomic Korean population is similar to that in personal annual medical check-ups. Risk factors for EE among them include old age, male sex, BMI > or = 25, current smoking, alcohol consumption, fasting glucose level > or = 126 mg/dL, and hiatal hernia.

Keyword

Erosive Esophagitis; Prevalence; Risk Factors; National Cancer Screening Program

MeSH Terms

Adult
Aged
Aged, 80 and over
Early Detection of Cancer
Endoscopy, Digestive System
Esophagitis/*epidemiology/pathology
Female
Humans
Male
Middle Aged
Multivariate Analysis
Prevalence
Republic of Korea/epidemiology
Retrospective Studies
Risk Factors
Socioeconomic Factors

Figure

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  Fig. 1 Endoscopic findings between subjects with and without erosive esophagitis (EE). Endoscopic findings were compared between the two groups. Prevalence of gastric ulcer (GU) and duodenal ulcer (DU) were not significantly different between the two groups. However, prevalence of endoscopically suspected esophageal metaplasia (ESEM) and hiatal hernia (HH) were significantly higher in subjects with EE than in those without.

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