Korean J Hepatol.  2007 Dec;13(4):565-570. 10.3350/kjhep.2007.13.4.565.

A Case of Fulminant Hepatic Failure Secondary to Hepatic Metastasis of Small Cell Lung Carcinoma

Affiliations
  • 1Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea. sheenj@hanmail.net
  • 2Department of Pathology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.

Abstract

Although liver metastasis is commonly found in cancer patients, fulminant hepatic failure secondary to diffuse cancer infiltration into the liver is rare. Liver metastasis-induced fulminant hepatic failure has been reported in patients with primary cancer of the gastrointestinal tract, breast and uroepithelium, and in patients with melanoma and hematologic malignancy. Small cell lung cancer is so highly invasive that hepatic metastasis is common, but rapid progression to fulminant hepatic failure is extremely rare. We report here on a case of a patient who died because of rapid progression to fulminant hepatic failure as a result of hepatic metastasis of small cell lung carcinoma.

Keyword

Liver failure, acute; Small cell carcinoma; Liver metastasis

MeSH Terms

Aged
Carcinoma, Small Cell/complications/pathology/*secondary
Female
Humans
Liver Failure, Acute/diagnosis/*etiology
Liver Neoplasms/complications/pathology/*secondary
Lung Neoplasms/complications/*pathology
Neoplasm Invasiveness
Tomography, X-Ray Computed
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