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Efficacy and safety of sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir for hepatitis C in Korea: a Phase 3b study

Heo J, Kim YJ, Lee SW, Lee YJ, Yoon KT, Byun KS, Jung YJ, Tak WY, Jeong SH, Kwon KM, Suri V, Wu P, Jang BK, Lee BS, Cho JY, Jang JW, Yang SH, Paik SW, Kim HJ, Kwon JH, Park NH, Kim JH, Kim IH, Ahn SH, Lim YS

Background/Aims: Despite the availability of direct-acting antivirals (DAAs) for chronic hepatitis C virus (HCV) infection in Korea, need remains for pangenotypic regimens that can be used in the presence of...
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Image-Guided Versus Conventional Brachytherapy for Locally Advanced Cervical Cancer: Experience of Single Institution with the Same Practitioner and Time Period

Lee TH, Kim KS, Kim HJ, Choi CH, Kang S, Eom KY, Wee CW, Song YS, Park NH, Kim JW, Chung HH, Kim HS, Lee M, Kang HC

Purpose This study aimed to compare treatment outcomes and toxicity profile between imaged-guided brachytherapy (IGBT) versus conventional brachytherapy (CBT) performed by the same practitioner during the same time period. Materials and...
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Effect of BRCA1/2 Mutational Status on Survival Outcomes According to Secondary Cytoreductive Surgery and Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer: A Real-World Evidence Study

Kim SI, Lim H, Kim HS, Chung HH, Kim JW, Park NH, Song YS, Lee M

Purpose This study aimed to investigate the impact of BRCA1/2 mutational status on survival outcomes in patients with platinum-sensitive relapsed (PSR) epithelial ovarian cancer (EOC). Materials and Methods We retrospectively identified...
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Simultaneous heart-kidney transplantation during mechanical circulatory support in a patient with bilateral iliac artery stenosis

Lee S, Song KS, Kim YS, Jang WS, Kim JB, Park NH, Park WY, Park UJ, Kim H, Kim IC

A 54-year-old male patient was admitted to the emergency room due to cardiac arrest. He had history of coronary artery bypass surgery 3 years ago. Despite the surgery and optimal...
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Diffusion-Weighted Imaging for Detecting Glufosinate Ammonium Intoxication: A Case Report

Kim HY, Park NH

Glufosinate ammonium-containing herbicides are non-selective herbicides, used worldwide. With the increasing use of glufosinate ammonium-containing herbicides, cases of acute intoxication in suicide attempts have also increased. Herein, we report a...
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Study on Educational Needs of Patient Safety Nursing Activities in Intensive Care Units: Utilizing Importance-Performance Analysis

Lee SH, Park NH

Purpose : The purpose of this study was to not only examine the importance and performance status of patient safety nursing activities in the intensive care unit but also to...
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Identification of Patients with Recurrent Epithelial Ovarian Cancer Who Will Benefit from More Than Three Lines of Chemotherapy

Seol A, Yim GW, Chung JY, Kim SI, Lee M, Kim HS, Chung HH, Kim JW, Park NH, Song YS

Purpose This study aimed to identify patients who would benefit from third and subsequent lines of chemotherapy in recurrent epithelial ovarian cancer (EOC). Materials and Methods Recurrent EOC patients who received...
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Tenofovir alafenamide treatment may not worsen the lipid profile of chronic hepatitis B patients: A propensity score-matched analysis

Jeong J, Shin JW, Jung SW, Park EJ, Park NH

Background/Aims: Tenofovir alafenamide (TAF) has shown less favorable effect on lipids compared to tenofovir disoproxil fumarate (TDF) in clinical trials. However, data regarding these outcomes in patients with chronic hepatitis...
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A Multi-Center, Double-Blind Randomized Controlled Phase III Clinical Trial to Evaluate the Antiviral Activity and Safety of DA-2802 (Tenofovir Disoproxil Orotate) and Viread (Tenofovir Disoproxil Fumarate) in Chronic Hepatitis B Patients

Kim HJ, Kim JH, Yeon JE, Seo YS, Jang JW, Cho YK, Jang BK, Han BH, Lee C, Lee JH, Yoon JH, Kim KM, Kim MY, Kim DY, Park NH, Cho EY, Lee JS, Lee JW, Kim IH, Song BC, Lee BS, Kwon OS

Background: Tenofovir disoproxil fumarate (TDF, Viread® ) had been used as a standard treatment option of chronic hepatitis B (CHB). This clinical trial was conducted to evaluate the efficacy and...
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Ultrasonographic Findings of a Chondrolipoma Arising from the Left Supraclavicular Region: A Case Report

Park NH, Jung YY

Chondrolipomas, which are lipomas with chondroid metaplasia, are rare benign soft tissue tumors with no relevant epidemiological reports or radiological information. A limited number of lipomas with osteo/chondroid differentiation have...
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Multiple Enhanced Lesions in the Brain MRI of a Patient with COVID-19

Kang YM, Park NH, Seong MJ, Han HJ, Jung YH

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Lymph Node Ratio Is a Strong Prognostic Factor in Patients with Early-Stage Cervical Cancer Undergoing Minimally Invasive Radical Hysterectomy

Kim SI, Kim TH, Lee M, Kim HS, Chung HH, Lee TS, Jeon HW, Kim JW, Park NH, Song YS

Purpose: To determine whether the prognostic impact of lymph node ratio (LNR), defined as the ratio between the number of positive lymph nodes and removed lymph nodes, differs between open...
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Germline and Somatic BRCA1/2 Gene Mutational Status and Clinical Outcomes in Epithelial Peritoneal, Ovarian, and Fallopian Tube Cancer: Over a Decade of Experience in a Single Institution in Korea

Kim SI, Lee M, Kim HS, Chung HH, Kim JW, Park NH, Song YS

Purpose This study aimed to present a single institutional experience with BRCA1/2 gene tests and the effects of pathogenic mutations in epithelial peritoneal, ovarian, and fallopian tube cancer (POFTC) on survival...
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A Complex Cortical Malformation Caused by a Mutation in the Tubulin-Encoding TUBB3 Gene

Lee YH, Park NH

Tubulinopathy commonly refers to complex congenital and non-progressive brain malformations caused by mutations in the tubulin genes. Among tubulin-encoding genes, TUBB3 has rarely been reported as a cause of complex...
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Influence of gender role conflict, resilience, and nursing organizational culture on nursing work performance among clinical nurses

Han JE, Park NH, Cho J

Purpose: The purpose of this study was to identify the factors influencing nursing work performance among clinical nurses in the hospital. Methods: This descriptive correlational study collected data from 122 clinical...
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Magnetic Resonance Imaging and Clinical Features of Chlorfenapyr-Induced Toxic Leukoencephalopathy: A Case Report

Kim JH, Park NH, Park JY, Kim SJ

Chlorfenapyr is widely used as an insecticide, despite it being fatal to humans. However, chlorfenapyr- induced central nervous system toxicity has rarely been reported. We report the magnetic resonance imaging...
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Low-level viremia and cirrhotic complications in patients with chronic hepatitis B according to adherence to entecavir

Lee SB, Jeong J, Park JH, Jung SW, Jeong ID, Bang SJ, Shin JW, Park BR, Park EJ, Park NH

Background/Aims: Low-level viremia (LLV) after nucleos(t)ide analog treatment was presented as a possible cause of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). However, detailed information on patients’...
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The Protective Effect of Ganoderma lucidum Extract in Ultraviolet B-Induced Human Dermal Fibroblasts and Skin Equivalent Models

Lee SH, Lee ES, Bae IH, Kim SH, Park NH, Shim JS, Lee CS, Lee J

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Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report

Kim JH, Park NH, Park JY, Kim SJ

We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst....
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Giant Intramyocardial Aneurysm in a Patient with Intercoronary Communication between the Left Circumflex Artery and Right Coronary Artery: A Case Report

Lee YH, Park NH, Park JY, Kim SJ

Coronary artery aneurysm is a rare disease. It occurs in the epicardial space, mostly along the course of major coronary arteries. Here, we report a case of a giant incidental...
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