J Korean Neurol Assoc.  2015 Feb;33(1):33-35.

Recurrent Transient Global Amnesia in a Hot and Humid Machinery Room

Affiliations
  • 1Departments of Neurology, Chungbuk National University College of Medicine, Cheongju, Korea. jissn@hanmail.net

Abstract

Transient global amnesia (TGA) is characterized by abrupt onset temporary dysfunction of anterograde and retrograde amnesia without other neurologic deficits. We encountered a 53-year-old man who developed recurrent TGA while working in a hot and humid machinery room (33degrees C and 64% relative humidity). Heat exposure and physical exertion may facilitate the leakage of cytokines into the systemic circulation so as to cause a cerebral endothelial insult. Functional insufficiency of the hippocampus and its connections caused by physical and environmental factors may be related to recurrent attacks.

Keyword

Transient global amnesia; Diffusion-weighted MRI; Hot and humid condition

MeSH Terms

Amnesia, Retrograde
Amnesia, Transient Global*
Cytokines
Hippocampus
Hot Temperature
Humans
Middle Aged
Neurologic Manifestations
Physical Exertion
Cytokines
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