Korean J Gastroenterol.  2009 Nov;54(5):279-284. 10.4166/kjg.2009.54.5.279.

Guidelines of Diagnosis for Peptic Ulcer Disease

Affiliations
  • 1Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Korea.
  • 2Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 4Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 5Department of Internal Medicine, Inje University College of Medicine, Busan, Korea. seolsymd@hanmail.net

Abstract

Peptic ulcer is one of the most prevalent diseases in gastrointestinal field. Recently, evolution was made for pathophysiology of peptic ulcer from "no acid, no ulcer" to Helicobacter pylori and non-steroidal anti-inflammatory drugs. The prevalence of peptic ulcer disease is estimated about 10% in Korea, and has declined due to Helicobacter pylori eradication therapy. Peptic ulcer has the cycle of exacerbation and improvement in the clinical course, and has not occasionally any clinical symptom. Helicobacter pylori eradication has made the marked reduction of relapse of peptic ulcer disease. Although nationwide endoscopic screening has enabled accurate diagnosis of peptic ulcer disease, general guideline for diagnosis of peptic ulcer has not made in Korea. Herein, we propose a guideline for the diagnosis of peptic ulcer according to domestic, international clinical studies, and experts opinions with level of evidence and grade of recommendation.

Keyword

Peptic ulcer; Guideline; Diagnosis

MeSH Terms

Anticoagulants/therapeutic use
Endoscopy, Gastrointestinal
Helicobacter Infections/diagnosis
Helicobacter pylori
Humans
Peptic Ulcer/*diagnosis
Proton Pump Inhibitors/therapeutic use

Cited by  3 articles

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Korean J Gastroenterol. 2020;76(3):108-133.    doi: 10.4166/kjg.2020.76.3.108.

Helicobacter pylori Eradication in Drug-related Peptic Ulcer
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Korean J Gastroenterol. 2020;76(5):227-231.    doi: 10.4166/kjg.2020.141.

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Korean J Gastroenterol. 2020;76(5):242-245.    doi: 10.4166/kjg.2020.138.


Reference

1. GRADE Working Group. Grading quality of evidence and strength of recommendations. BMJ. 2004; 328:1490–1494.
2. Yuan Y, Hunt RH. Treatment of non-NSAID and non-H. pylori gastroduodenal ulcers and hypersecretory states. Wolfe MM, editor. ed.Therapy of digestive disorders. 2nd ed.London, UK: Elsevier;2006. p. 315–336.
3. Tummala S, Keates S, Kelly CP. Update on the immunologic basis of Helicobacter pylori gastritis. Curr Opin Gastroenterol. 2004; 20:592–597.
4. Dore MP, Graham DY. Pathogenesis of duodenal ulcer disease: the rest of the story. Ballieres Best Pract Res Clin Gastroenterol. 2000; 14:97–107.
Article
5. Laine L. Nonsteroidal anti-inflammatory drug gastropathy. Gastrointest Endosc Clin N Am. 1996; 6:289–504.
Article
6. Wolfe MM, Soll AH. The physiology of gastric acid secretion. N Engl J Med. 1988; 319:1707–1715.
Article
7. Levine MS. Role of the double-contrast upper gastrointestinal series in the 1990s. Gastroenterol Clin North Am. 1995; 24:289–308.
Article
8. Levine MS, Creteur V, Kressel HY, Laufer I, Herlinger H. Benign gastric ulcers: diagnosis and follow-up with double-contrast radiography. Radiology. 1987; 164:9–13.
Article
9. Grossman MI. The Veterans Administration Cooperative Study on Gastric Ulcer. 10. Resume and comment. Gastroenterology. 1971; 61(suppl 2):S635–S638.
10. Sakita T, Fukutomi H. Endoscopic diagnosis. Yoshitoshi Y, editor. ed.Ulcer of stomach and duodenum. 1st ed.Tokyo: Nankodo;1971. p. 198–208.
11. Misumi A, Mori K, Ikeda T, et al. Evaluation of fiber-gastroscopic biopsy in the diagnosis of gastric cancer: a study of 339 cases. Gastroenterol Jpn. 1978; 13:255–263.
Article
12. Moon YM, Kang JK, Park IS, Choi HJ. Diagnostic value of forward view endoscopic biopsy in gastric cancer. Korean J Med. 1977; 20:413–422.
13. Graham DY, Schwartz JT, Cain DG, Gyorkey F. Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma. Gastroenterology. 1982; 82:228–231.
Article
14. Im JP, Kim SG, Kim JS, Jung HC, Song IS. Time-dependent morphological change of depressed-type early gastric cancer. Surg Endosc. 2009. (in press).
15. Kang HY, Kim N, Park YS, et al. Progression of atrophic gastritis and intestinal metaplasia drives Helicobacter pylori out of the gastric mucosa. Dig Dis Sci. 2006; 51:2310–2315.
16. Yoo JY, Kim N, Park YS, et al. Detection rate of Helicobacter pylori against a background of atrophic gastritis and/or intestinal metaplasia. J Clin Gastroenterol. 2007; 41:751–755.
17. Son JW, Han SY, Choi SY, Shin WW, Hong SH, Han JY. Comparison of simple diagnostic methods for Helicobacter pylori gastritis. Korean J Intern Med. 1994; 46:62–71.
18. Lee WJ, Kim JG, Kim YT, et al. Evaluation of serological diagnosis for Helicobacter pylori infection. Korean J Gastroenterol. 1994; 26:631–636.
19. Hong SP, Park HJ, Park IS, Lee KW, Kim HG. Serological diagnosis of Helicobacter pylori infection comparison of diagnostic values between HM-CAP (EPI) and GAP (Bio-Rad) test. Korean J Gastroenterol. 1995; 27:167–173.
20. Kim SY, Ahn JS, Ha YJ, et al. Serodiagnosis of Helicobacter pylori infection in Korean patients using enzyme-linked immunosorbent assay. J Immunoassay. 1998; 19:251–270.
21. Lee JH, Kim N, Chung JI, et al. Longterm follow up of Helicobacter pylori IgG serology after eradication and reinfection rate of H. pylori in South Korea. Helicobacter. 2008; 13:288–294.
22. Lahner E, Bordi C, Di Giulio E, et al. Role of Helicobacter pylori serology in atrophic body gastritis after eradication treatment. Aliment Pharmacol Ther. 2002; 16:507–514.
23. Ito M, Tanaka S, Kim S, et al. A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: a multicenter study. J Gastroenterol Hepatol. 2005; 20:1241–1245.
24. Kato S, Ozawa K, Okuda M, et al. Accuracy of the stool antigen test for the diagnosis of childhood Helicobacter pylori infection: a multicenter Japanese study. Am J Gastroenterol. 2003; 98:296–300.
25. Ho CY, Chen TS, Chang FY, Lee SD. Rapid urease test from non-ulcer part of stomach is superior to histology from ulcer in detection of Helicobacter pylori infection in patients with gastric ulcer. Hepatogastroenterology. 2004; 51:1877–1880.
26. Lee SW. Diagnosis of Helicobacter pylori infection. Korean J Gastroenterol. 2005; 46:166–171.
27. Vakil N, Vaira D. Non-invasive tests for the diagnosis of infection. Rev Gastroenterol Disord. 2004; 4:1–6.
28. Nishikawa K, Sugiyama T, Kato M, et al. A prospective evaluation of new rapid urease tests before and after eradication treatment of Helicobacter pylori, in comparison with histology, culture and 13C-urea breath test. Gastrointest Endosc. 2000; 51:164–168.
29. Perri F, Maes B, Geypens B, Ghoos Y, Hiele M, Rutgeerts P. The influence of isolated doses of drugs, feeding and colonic bacterial ureolysis on urea breath test results. Aliment Pharmacol Ther. 1995; 9:705–709.
Article
30. Prince MI, Osborne JS, Ingoe L, Jones DE, Cobden I, Barton JR. The CLO test in the UK: inappropriate reading and missed results. Eur J Gastroenterol Hepatol. 1999; 11:1251–1254.
31. Bilardi C, Biagini R, Dulbecco P, et al. Stool antigen assay (HpSA) is less reliable than urea breath test for post-treatment diagnosis of Helicobacter pylori infection. Aliment Pharmacol Ther. 2002; 16:1733–1738.
32. Guell M, Artigau E, Esteve V, Sanchez-Delgado J, Junquera F, Calvet X. Usefulness of a delayed test for the diagnosis of Helicobacter pylori infection in bleeding peptic ulcer. Aliment Pharmacol Ther. 2006; 23:53–59.
33. Tang JH, Liu NJ, Cheng HT, et al. Endoscopic diagnosis of Helicobacter pylori infection by rapid urease test in bleeding peptic ulcers: a prospective case-control study. J Clin Gastroenterol. 2009; 43:133–139.
34. Griñó P, Pascual S, Such J, et al. Comparison of diagnostic methods for Helicobacter pylori in patients with upper gastrointestinal bleeding. Scand J Gastroenterol. 2001; 36:1254–1258.
35. Gisbert JP, Abraira V. Accuracy of of Helicobacter pylori diagnostic tests in patients with bleeding peptic ulcer: a systematic review and metaanalysis. Am J Gastroenterol. 2006; 101:848–863.
36. Eisen GM, Baron TH, Dominitz JA, et al. American Society for Gastrointestinal Endoscopy. Guideline on the management of anticoagulation and antiplatelet therapy for endoscopic procedures. Gastrointest Endosc. 2002; 55:775–779.
37. Kimchi NA, Broide E, Scapa E, Birkenfeld S. Antiplatelet therapy and the risk of bleeding induced by gastrointestinal endoscopic procedures. A systematic review of the literature and recommendations. Digestion. 2007; 75:36–45.
38. Zuckerman MJ, Hirota WK, Adler DG, et al: Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy. ASGE guideline: the management of low-molecular-weight heparin and nonaspirin antiplatelet agents for endoscopic procedures. Gastrointest Endosc. 2005; 61:189–194.
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