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Korean J Gastroenterol.  2016 Jun;67(6):318-320. 10.4166/kjg.2016.67.6.318.

Diagnosis and Treatment of Peptic Ulcer Disease: Present and Future Perspective

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. gastro@catholic.ac.kr

Abstract

Peptic ulcer disease is one of the most commonly encountered diseases in gastroenterology clinics. After the discovery of Helicobacter pylori by Warren and Marshall, it has been identified as the most important cause of peptic ulcer. Eradication of H. pylori markedly reduces the post-treatment recurrence rate of peptic ulcer. However, as human populations age, the incidence of cardiovascular and musculoskeletal diseases increases and consequent use of aspirin and non-steroidal anti-inflammatory drugs increases. Thus causes and presenting patterns of peptic ulcer have changed. In this review, I describe new diagnostic and therapeutic strategies for peptic ulcer disease and explore future perspectives.

Keyword

Peptic ulcer disease; Diagnosis; Treatment

MeSH Terms

Aspirin
Diagnosis*
Gastroenterology
Helicobacter pylori
Humans
Incidence
Musculoskeletal Diseases
Peptic Ulcer*
Recurrence
Aspirin
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