Korean J Gastroenterol.  2008 May;51(5):305-308.

Spontaneous Resolution of Multiple Fundic Gland Polyps after Cessation of Treatment with Omeprazole

Affiliations
  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. chs@catholic.ac.kr

Abstract

Fundic gland polyps (FGPs) are the most common type of gastric polyps, found primarily in the fundus and body of stomach. Long term use of proton pump inhibitor (PPI) is known to be associated with certain histological changes of the normal gastric mucosa including parietal cell hyperplasia and fundic gland cysts. We experienced a patient who showed spontaneous resolution of multiple FGPs after the cessation of omeprazole. Two years ago, the patient showed only endoscopically confirmed erosive esophagitis without FGPs. Multiple FGPs developed one year after the use of omeprazole and spontaneously disappeared with the cessation of omeprazole.

Keyword

Fundic gland polyp; Proton pump inhibitor; Microcyst

MeSH Terms

Aged
Anti-Ulcer Agents/therapeutic use
Gastric Fundus/pathology
Humans
Male
Omeprazole/*adverse effects
Polyps/*chemically induced/*diagnosis
Stomach Neoplasms/*chemically induced/*diagnosis
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