Korean J Med.  2001 Aug;61(2):178-183.

A case of primary empty sella syndrome combined with Cushing's disease

• Park HJ
• Jung J
• Lee KH
• Kim JU
• Cho JW
• Moon SD
• Son HS
• Yoon KH
• Cha BY
• Lee KW
• Son HY
• Kang SK

Abstract

Empty sella is defined as a sella which, regardless of its size, is completely or partly filled with cerebrospinal fluid (CSF), and is divided into two groups, primary or secondary. Secondary empty sella syndrome is associated with a prior surgery, radiation therapy or medical treatment of pituitary gland, and otherwise primary. The endocrine function of primary empty sella syndrome is usually normal, but sometimes, this syndrome is associated with complete or partial pituitary insufficiency and rarely pituitary hypersecretion. In the cases of hypersecretion of pituitary hormones, hyperprolactinemia, acromegaly and hypersecretion of adrenocorticotrophin (ACTH) has been reported. but, hypersecretion of ACTH is rarely reported. We describe a patient of primary empty sella syndrome combined with Cushing's disease. So we present this case with a review of the literature.

Keyword

Empty sella syndrome; Cushing's syndrome

MeSH Terms

Acromegaly
Adrenocorticotropic Hormone
Cerebrospinal Fluid
Cushing Syndrome
Empty Sella Syndrome*
Humans
Hyperprolactinemia
Hypopituitarism
Pituitary Gland
Pituitary Hormones
Adrenocorticotropic Hormone
Pituitary Hormones