J Korean Soc Endocrinol.  1996 Dec;11(4):517-522.

Two Cases of Graves Disease Associated The Empty Sella Syndrome

• Choi YJ
• Kim HS
• Park ER
• Shin YG
• Chung CH

Abstract

The empty sella syndrome is characterized by obesity, frequent pregnancy, headache and high blood pressure, but its exact cause remains unknown. Usually the incomplete diaphragmatic sella has been considered as the cause of the empty sella syndrome, but some authors recently have suggested that the antipituitary antibody way be related to development of pituitary atrophy and the pituitary empty sella syndrome, and thus it may be clinically useful as screening test for the empty sella syndrome. We experienced two empty sella syndromes associated Graves disease and applied the antipituitary antibody as the diagnostic tool of the empty sella syndrome. But none of this two patients had antipituitary antibody and we report these cases with reviews of literatures.

MeSH Terms

Atrophy
Empty Sella Syndrome*
Graves Disease*
Headache
Humans
Hypertension
Mass Screening
Obesity
Pregnancy