Korean J Dermatol.  2005 Feb;43(2):228-232.

A Case of Reiter's Syndrome

• Yi JH
• Choi HS
• Park SH
• Yun SK
• Ihm CW
• Kim HU

Abstract

Reiter's syndrome is a multisystemic disease characterized by a triad of urethritis, conjunctivitis and arthritis in association with skin lesions such as keratoderma blenorrhagica and balanitis circinata. Most cases of Reiter's syndrome are closely related to HLA-B27. We present a case of Reiter's syndrome that has typical clinicopathologic characteristics. A 37-year-old man had experienced weight loss and polyarthralgia for 7 months. He had painful swelling on the shoulders, elbows and knee joints, and hyperkeratotic plaques all over his body. He had no history of dysentry or sexual exposure, but was associated with the HLA-B27 antigen. Histopathology of the skin lesions on the back showed hyperkeratosis, rete ridge elongation and Munro microabscess. He was treated with corticosteroids, sulfasalazine, methotrexate, topical steroids and intra-articular corticosteroid injections. His skin lesions and urethritis were improved after 1 week, and his arthritis was improved after 6 months of therapy.

Keyword

Reiter's syndrome; HLA-B27

MeSH Terms

Adrenal Cortex Hormones
Adult
Arthralgia
Arthritis
Balanitis
Conjunctivitis
Elbow
HLA-B27 Antigen
Humans
Knee Joint
Male
Methotrexate
Shoulder
Skin
Steroids
Sulfasalazine
Urethritis
Weight Loss
Adrenal Cortex Hormones
HLA-B27 Antigen
Methotrexate
Steroids
Sulfasalazine