A Case of Cronkhite-Canada Syndrome

Chung, Sung Tae; Chung, Eul Chang; Choi, Jee Ho; Sung, Kyung Jeh; Moon, Kee Chan; Koh, Jai Kyoung

Abstract

The Cronkhite-Canada syndrome is a rare, non-neoplastic, non-hereditary condition which consists of gastrointestinal polyposis associated with alopecia, onychodystrophy and hyperpigmentation of the skin. It usually encountered with severe diarrhea, weight loss and other malabsorption symptoms. The etiology of the condition is unknown. Usually, this syndrome is associated with a poor prognosis due to the effect of malabsorption and generalized debility. We report a case of this syndrome showing unusually rapid improvement after 3-month following only conservative treatment. To our knowledge, this is the first case report of Cronkhite-Canada syndrome in the Karean dermatologic literature.