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Exploratory Study of Epidermis, Basement Membrane Zone, Upper Dermis Alterations and Wnt Pathway Activation in Melasma Compared to Adjacent and Retroauricular Skin

Espósito , Brianezi G, de Souza N, Miot LD, Miot HA

BACKGROUND: Melasma is a chronic acquired focal hypermelanosis which pathogenesis has not been fully elucidated. Classical pathophysiologic studies have analysed the affected and perilesional areas, but little is known about...
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Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate

Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ

Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS...
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A Split-Face, Single-Blinded, Randomized Controlled Comparison of 532 nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser versus 532 nm Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser in the Treatment of Solar Lentigines

Kim JY, Yang J, Huh G, Choi YJ, Kim WS

BACKGROUND: Solar lentigines are the most common form of benign epidermal pigmentation and one of the major cosmetic concerns in Korea. A 532 nm Q-switched neodymium: yttrium-aluminum-garnet (QSND) laser is...
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Anti-melanogenesis and Anti-inflammatory Effects of Cinnamomi Cortex Extract In Vitro

Park JH, Park SJ, Park KY, Kim BJ

  • KMID: 2465952
  • Korean J Dermatol.
  • 2019 Sep;57(8):448-456.
BACKGROUND: Many researchers have sought to identify safe, natural herbal extracts that exert an anti-melanogenesis effect. Cinnamomi cortex has been widely used as a herbal medicine in Asia and Europe. OBJECTIVE:...
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'Need of the Hour': Early Diagnosis and Management of Multidrug Resistant Tuberculosis of the Spine: An Analysis of 30 Patients from a “High Multidrug Resistant Tuberculosis Burden” Country

Arockiaraj J, Karthik R, Michael JS, Amritanand R, David KS, Krishnan V, Sundararaj GD

STUDY DESIGN: Retrospective study. PURPOSE: To report the prevalence of patients with multidrug-resistant (MDR) tubercular spondylodiscitis and their outcomes. Additionally, to assess the role of Xpert MTB/RIF assay in early detection...
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Heat-related skin disease

Kim KH

Skin disease can be caused by high temperature, and it is related to the temperature regulation mechanism of human body, adaptation reaction to temperature change, and health problems due to...
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Analysis of Clinical Features and Treatment Outcomes Using 1,064-nm Nd-YAG Laser with Topical Hydroquinone in Patients with Riehl's Melanosis: A Retrospective Study in 10 Patients

Choi CW, Jo G, Lee DH, Jo SJ, Lee C, Mun JH

BACKGROUND: Hyperpigmentation on the face and neck can be a devastating psychological burden in patients with Riehl's melanosis. However, successful treatment of the disease is challenging for clinicians. OBJECTIVE: To evaluate...
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A Clinical and Histopathological Review of Chronic Cutaneous Lupus Erythematosus Alopecia in Korea

Chae MH, Lee JY, Yoon TY

  • KMID: 2440724
  • Korean J Dermatol.
  • 2019 Feb;57(2):66-75.
BACKGROUND: Chronic cutaneous lupus erythematosus (CCLE) often affects the scalp and results in alopecic lesions. To date, no studies have examined CCLE alopecia in Korea. OBJECTIVE: The aim of this study...
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Hyperpigmentation of Both Hands due to Vitamin B12 Deficiency

Son JH, Jin H, You H, Shim WH, Kim GW, Kim HS, Ko HC, Kim MB, Kim BS

  • KMID: 2436851
  • Korean J Dermatol.
  • 2018 Aug;56(7):455-456.
No abstract available.
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Non-cultured Epidermal Cell Suspension Transplantation Using Suction Blisters to Treat Refractory Vitiligo: A Retrospective Study of 20 Cases

Bae JM, Jung HM, Lee HN, Lee RW, Eun SH, Kwon HS, Lee JH, Kim GM

  • KMID: 2436845
  • Korean J Dermatol.
  • 2018 Aug;56(7):426-432.
BACKGROUND: As nonsurgical interventions for vitiligo are not always successful, various surgical modalities have been used in patients with refractory vitiligo. Of these, non-cultured epidermal suspension transplantation (NCES) was recently...
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Effective Treatment for Post-inflammatory Hyperpigmentation Caused by Cosmetic Procedures

Lim Y, Lee JH

  • KMID: 2436736
  • Korean J Dermatol.
  • 2018 Jul;56(6):363-367.
BACKGROUND: Postinflammatory hyperpigmentation (PIH) is one of the most common adverse effects associated with dermatologic procedures, especially those for cosmetic purposes. Low fluence Q-Switched Nd:YAG laser (LFQS) has been widely...
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Pigmented Extramammary Paget's Disease on the Scrotum

Kang IH, Jeong KH, Shin MK, Lee MH

  • KMID: 2436715
  • Korean J Dermatol.
  • 2018 Jun;56(5):353-355.
No abstract available.
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Progressive Cribriform and Zosteriform Hyperpigmentation: A Case Series and Review of the Literature

Lee SK, Suh JH, Kim MS, Lee UH

  • KMID: 2436708
  • Korean J Dermatol.
  • 2018 Jun;56(5):338-342.
Progressive cribriform and zosteriform hyperpigmentation (PCZH) is a distinctive pigmentary disorder observed along the lines of Blaschko. Clinically, the lesions appear as uniformly tan, cribriform macular hyperpigmentation with a zosteriform...
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The effects of green tea (Camellia sinensis) flower extracton melanin synthesis in B16-F10 melanoma cells

Dissanayake CY, Moon HH, Yang KM, Lee Y, Han CH

The present study observed the effects of a green tea (Camellia sinensis) flower extract (GTFE) on melanin synthesis in B16-F10 melanoma cells. GTFE exhibited antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl and inhibited...
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A Case of Sexual Enhancer Induced Fixed Drug Eruption

Lee SK, Kim DJ, Suh JH, Kim MS, Lee UH

  • KMID: 2436688
  • Korean J Dermatol.
  • 2018 May;56(4):269-272.
Fixed drug eruption is a commonly reported mucocutaneous drug eruption. A 61-year-old male presented to our clinic with a complaint of an itchy round erythematous patch on the left hand...
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Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway

Ko GA, Shrestha S, Kim Cho S

BACKGROUND/OBJECTIVES: Sageretia thea is traditionally used as a medicinal herb to treat various diseases, including skin disorders, in China and Korea. This study evaluated the inhibitory effect of Sageretia thea...
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The Efficacy of a Q-Switched 694-nm Ruby Fractional Laser for Treating Acquired Bilateral Nevus of Ota-Like Macules

Lee SJ, Nam SM, Cha HG, Park ES, Kim YB

BACKGROUND: Acquired bilateral nevus of Ota-like macules (ABNOM) are a common form of hyperpigmentation in Asian populations, characterized by brownish-blue or slate-gray pigmentation in the bilateral malar regions. The purpose...
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Asymptomatic Hyperpigmentation without Preceding Inflammation as a Clinical Feature of Citrus Fruits-Induced Phytophotodermatitis

Choi JY, Hwang S, Lee SH, Oh SH

Phytophotodermatitis is a condition that occurs by contact with plants containing phototoxic agents such as furocoumarins and psoralens with subsequent ultraviolet exposure. Phytophotodermatitis typically presents as sharply defined erythematous patches...
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Early Debridement and Cultured Allogenic Keratinocyte Dressing Prevent Hypertrophic Scarring in Infants with Deep Dermal Burns

Joo HS, Lee SJ, Sung KY

BACKGROUND: Deep dermal burns are frequently treated with excision and skin grafting. Otherwise, wound healing may take up to 4 to 6 weeks, with serious scarring. Especially in pediatric patients,...
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Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway

Ko GA, Kim Cho S

Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent....
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