Korean J Gastrointest Endosc.  2000 Aug;21(2):658-661.

A Case of Diffusely Infiltrating Primary Colon Cancer

Affiliations
  • 1Department of Internal Medicine, Ulsan Universaty Hospital, Ulsan, Korea.
  • 2Department of General Surgery, Ulsan Universaty Hospital, Ulsan, Korea.
  • 3Department of Diagnostic Pathology, Ulsan Universaty Hospital, Ulsan, Korea.

Abstract

Diffusely infiltrating primary colorectal carcinoma is a rare disease. This type of carcinoma extensively spreads beneath the mucosal layer. Clinically, it resembles inflammatory colorectal disease and metastatic carcinoma and is difficult to diagnosis. Moreover, the prognosis is extremely poor. A 66-year-old man was admitted to our hospital because of lower abdominal pain. Barium enema showed circumferential long segment narrowing in the proximal sigmoid colon without definite mass or ulceration and abdominal CT demonstrated colonic wall thickening. So it was diagnosed as inflammatory condition by image study. Colonoscopic examination showed hypertrophied mucosa and luminal narrowing on the 40 cm from the anal verge, but the oral side couldn't be examined because of stenosis. Biopsy revealed poorly differentiated adenocarcinoma, and left hemicolectomy was done. The pathology showed diffusely infiltrating adenocarcinoma with metastasis in regional lymph node and mesentry involvement.

Keyword

Colorectal cancer; Diffusely infiltrating cancer

MeSH Terms

Abdominal Pain
Adenocarcinoma
Aged
Barium
Biopsy
Colon*
Colon, Sigmoid
Colonic Neoplasms*
Colorectal Neoplasms
Constriction, Pathologic
Diagnosis
Enema
Humans
Lymph Nodes
Mucous Membrane
Neoplasm Metastasis
Pathology
Phenobarbital
Prognosis
Rare Diseases
Tomography, X-Ray Computed
Ulcer
Barium
Phenobarbital
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