Korean J Nucl Med.  2003 Feb;37(1):13-23.

PET studies in Alzheimer Disease and Other Degenerative Dementias

Affiliations
  • 1Department of Neurology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Korea.

Abstract

Neurodegenerative disorders cause a variety of dementia including Alzheimer disease, frontotemporal dementia, dementia with Lewy bodies, corticobasal degeneration, progressive supranuclear palsy, and Huntington's disease. PET scan is useful for early detection and differential diagnosis of these dementing disorders. Also, it provides valuable information about clinico-anatomical correlation, allowing better understanding of function of brain. Here we discuss recent achievements PET studies regarding these dementing disorders. Future progress in PET technology, new tracers, and image analysis will play an important role in further clarifying the disease pathophysiology and brain functions.

Keyword

PET; dementia; Alzheimer disease; frontotemporal dementia; dementia with Lewy bodies; corticobasal degeneration; progressive supranuclear palsy; Huntington disease

MeSH Terms

Alzheimer Disease*
Brain
Dementia*
Diagnosis, Differential
Frontotemporal Dementia
Huntington Disease
Lewy Bodies
Neurodegenerative Diseases
Positron-Emission Tomography
Supranuclear Palsy, Progressive
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