J Korean Soc Transplant.  2013 Sep;27(3):138-142. 10.4285/jkstn.2013.27.3.138.

Posttransplant Lymphoproliferative Disorder without Epstein-Barr Virus Presented as Small Bowel Perforation in Renal Transplant Recipient: A Case Report

Affiliations
  • 1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. jakii@yuhs.ac

Abstract

Posttransplant lymphoproliferative disorder (PTLD) is documented as one of the serious complications leading to mortality particularly in organ transplant recipients receiving immunosuppressive therapy. Extant literature confirms beyond doubt that the most common site of involvement of PTLD is lymph nodes, and rarely involved is the gastrointestinal tract. It is a well-known fact that Epstein-Barr virus (EBV) is a risk factor for PTLD development. In this study, we report a case of PTLD presented as small bowel perforation without EBV infection after long-term immunosuppressive therapy in a renal transplant recipient.

Keyword

Posttransplant lymphoproliferative disease; Small bowel perforation; Kidney transplantation

MeSH Terms

Epstein-Barr Virus Infections
Gastrointestinal Tract
Herpesvirus 4, Human
Kidney Transplantation
Lymph Nodes
Lymphoproliferative Disorders
Risk Factors
Transplants
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