Clin Exp Otorhinolaryngol.  2012 Dec;5(4):240-242. 10.3342/ceo.2012.5.4.240.

A "Boxer Glove" Contoured Laryngeal Amyloidosis

• Lee EJ
• Yang YS
• Kim JS
• Hong KH

• KMID: 1489087
• DOI: http://doi.org/10.3342/ceo.2012.5.4.240

Abstract

Laryngeal amyloidosis is uncommon and poorly understood, with limited long-term studies. Although primary localized laryngeal amyloidosis is extremely rare, it frequently involves the ventricles and the false and true vocal cords. We present a 58-year-old woman with localized laryngeal amyloidosis who presented no symptoms. On indirect laryngoscopic examination, the mass involved both arytenoids only, and had a likeness to a "boxer glove." She was treated surgically by microlaryngoscopy under general anesthesia and the mass was excised using a carbon dioxide laser. We present this case and a review of literature.

Keyword

Amyloidosis; Larynx

MeSH Terms

Amyloidosis
Anesthesia, General
Female
Humans
Larynx
Lasers, Gas
Middle Aged
Vocal Cords

Figure

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  Fig. 1 (A) Fiberoptic laryngoscopy revealed two yellowish masses located on the apices of both arytenoid cartilages. (B) Two month follow-up fiberoptic laryngoscopy revealed a nearly clean state.

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  Fig. 2 (A) Subepithelial deposition of acellular, eosinophilic, and amorphous materials (H&E, ×200). (B) Amyloid was identified as Congo red-positive material with apple-green birefringence in polarized light. (C) Electron microscopy showed linear, non-branching, fibrillar amyloid materials.

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