Korean J Otorhinolaryngol-Head Neck Surg.  2022 May;65(5):293-295. 10.3342/kjorl-hns.2022.00038.

A Case of Glottic Amyloidosis Presenting as Leukoplakia

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Veterans Health Service Medical Center, Seoul, Korea
  • 2Department of Pathology, Veterans Health Service Medical Center, Seoul, Korea

Abstract

Amyloidosis is defined as a deposit of amyloid substance. While it rarely occurs in the head and neck region, it is most commonly found in the larynx. Laryngeal amyloidosis can occur in the false vocal cord, ventricle, and glottis etc. The typical feature of laryngeal amyloidosis is a round yellowish submucosal mass. A 72-year-old male presented with voice change that began a couple of years ago. The rigid laryngoscopy showed a whitish patch in the medial and superior surfaces of the left true vocal fold. He was pathologically diagnosed with amyloidosis by laryngeal microsurgery. With a relevant review of literature, we report this case as it demonstrates rare, atypical features of laryngeal amyloidosis.

Keyword

Amyloidosis; Leukoplakia; Vocal cords
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