J Korean Soc Radiol.  2010 Apr;62(4):339-341. 10.3348/jksr.2010.62.4.339.

Laryngeal Amyloidosis Mimicking Glottic Cancer: A Case Report

Affiliations
  • 1Department of Radiology, College of Medicine, The Catholic University of Korea, Korea. jeeyoungkim@catholic.ac.kr
  • 2Department of Otorhinolaryngology, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea.

Abstract

Amyloidosis is a slowly progressive, benign disease that is characterized by the extracellular deposition of fibrillar proteins in many different tissues and organs throughout the body. Primary amyloidosis can be subdivided into the systemic and localized forms. The localized form is less common than the systemic form and the larynx is the most frequently affected site. The importance of laryngeal amyloidosis lies in its possible confusion with glottic cancer because of the clinical feature. We report here on a case of laryngeal amyloidosis in a 47-year-old man who suffered from progressive dyspnea.


MeSH Terms

Amyloidosis
Dyspnea
Humans
Laryngeal Diseases
Larynx
Middle Aged
Proteins
Amyloidosis
Proteins

Figure

  • Fig. 1 A 47-year-old man with laryngeal amyloidosis. A. Direct laryngoscopy shows polypoid masses with smooth surfaces involving both the true and false vocal cords. B. The axial neck CT scan shows diffuse soft-tissue thickening involving both vocal cords, and this mimics vocal cord carcinoma. C, D. The axial T1 (C) and T2-weighted images (D) of neck MRI show diffuse thickening along both vocal cords with hypointensity. E. The axial contrast enhanced T1-weighted image (E) shows homogenous enhancement of the thickened true vocal cord.


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