Lab Anim Res.  2011 Dec;27(4):347-351. 10.5625/lar.2011.27.4.347.

Uterine adenocarcinoma with feline leukemia virus infection

  • 1Center for Animal Resources Development, Wonkwang University, Iksan,
  • 2Family Animal Clinic, Gunsan, Korea.
  • 3Institute of Biotechnology, Wonkwang University, Iksan, Korea.


Feline endometrial adenocarcinomas are uncommon malignant neoplasms that have been poorly characterized to date. In this study, we describe a uterine adenocarcinoma in a Persian cat with feline leukemia virus infection. At the time of presentation, the cat, a female Persian chinchilla, was 2 years old. The cat underwent surgical ovariohystectomy. A cross-section of the uterine wall revealed a thickened uterine horn. The cat tested positive for feline leukemia virus as detected by polymerase chain reaction. Histopathological examination revealed uterine adenocarcinoma that had metastasized to the omentum, resulting in thickening and the formation of inflammatory lesions. Based on the histopathological findings, this case was diagnosed as a uterine adenocarcinoma with abdominal metastasis. To the best of our knowledge, this is the first report of a uterine adenocarcinoma with feline leukemia virus infection.


Uterus; adenocarcinoma; feline leukemia virus; cat
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