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Effect of Xenogeneic Substances on the Glycan Profiles and Electrophysiological Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Kim YG, Yun JH, Park JW, Seong D, Lee Sh, Park KD, Lee HA, Park M

Background and Objectives: Human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte (CM) hold great promise as a cellular source of CM for cardiac function restoration in ischemic heart disease. However, the use...
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Transarterial Chemoembolization for Hepatocellular Carcinoma: 2023 Expert Consensus-Based Practical Recommendations of the Korean Liver Cancer Association

Cho Y, Choi JW, Kwon H, Kim KY, Lee BC, Chu HH, Lee DH, Lee HA, Kim GM, Oh JS, Hyun D, Lee IJ, Rhim H, Research Committee of the Korean Liver Cancer Association

Transarterial chemoembolization (TACE) was introduced in 1977 with the administration of chemotherapeutic agent to gelatin sponge particles through the hepatic artery in patients with hepatocellular carcinoma (HCC) and was established...
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Standardized Suicide Prevention Program for Gatekeeper Intervention of North Korean Defectors in South Korea

Lee YJ, Lee HA, Kim KA, Baik M, Paik JW, Seol J, Lee SM, Lee EJ, Lee H, Lim M, Jun JY, Ki SW, Jeon HJ, Kwon SJ, Lee HY

Objective North Korean defectors (NKDs) have experienced substantial difficulties during the migration and settlement in South Korea. They have a high prevalence of depression, post-traumatic stress disorder, and suicidal behaviors....
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The Effectiveness of Virtual Reality Intervention for COVID-19-Related Psychological Distress: A Systematic Review

Lee SA, Heo S, Kim S, Park C, Jung Y, Ji G, Lee HA, Kim K, Kim S, Kim BN, Kim JS

Objective The prolonged coronavirus disease-2019 (COVID-19) pandemic is likely to cause psychological distress in people. This systematic review aimed to identify the effectiveness of virtual reality (VR)-based psychological intervention among...
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Influence of Wearing a Face Mask on Subjective Communication Difficulties According to Hearing Level

Lee HA, Lee SJ, Lee SH, Chung JH, Byun H

Background and Objectives The aim of this study was to assess the effect of wearing face masks on communication according to hearing levels using a questionnaire. Subjects and Method Individuals who...
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Long-term prognosis and the need for histologic assessment of chronic hepatitis B in the serological immune-tolerant phase

Yoo JJ, Park SY, Moon JE, Lee YR, Lee HA, Lee J, Kim YS, Seo YS, Kim SG

Background/Aims: The histologic status of the immune-tolerant (IT) phase of chronic hepatitis B relative to long-term outcomes is unclear. This study aimed to discover how the serological criteria currently in...
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Current status of ultrasonography in national cancer surveillance program for hepatocellular carcinoma in South Korea: a large-scale multicenter study

Yoo SH, Kim SS, Kim SG, Kwon JH, Lee HA, Seo YS, Jung YK, Yim HJ, Song DS, Kang SH, Kim MY, Ahn YH, Han J, Kim YS, Chang Y, Jeong SW, Jang JY, Yoo JJ

Background/Aim: Abdominal ultrasonography (USG) is recommended as a surveillance test for high-risk groups for hepatocellular carcinoma (HCC). This study aimed to analyze the current status of the national cancer surveillance...
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Age, Sex, and Body Mass Index Should Be Considered When Assessing Spleen Length in Patients with Compensated Advanced Chronic Liver Disease

Lee HA, Kim SU, Lim J, Kim MY, Kim SG, Suk KT, Jang JY, An H, Yim HJ, Seo YS

Background/Aims: We investigated the factors related to spleen length and the diagnostic accuracy of a model using spleen length corrected by related factors, for the prediction of varices needing treatment...
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Noninvasive imaging biomarkers for liver fibrosis in nonalcoholic fatty liver disease: current and future

Yu JH, Lee HA, Kim SU

Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent worldwide and becoming a major cause of liver disease-related morbidity and mortality. The presence of liver fibrosis in patients with NAFLD is...
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Clinical outcomes of acute upper gastrointestinal bleeding according to the risk indicated by Glasgow-Blatchford risk score-computed tomography score in the emergency room

Lee HA, Jung HK, Kim TO, Byeon JR, Jeong ES, Cho HJ, Tae CH, Moon CM, Kim SE, Shim KN, Jung SA

Background/Aims: Acute upper gastrointestinal (UGI) bleeding is a significant emergency situation with a mortality rate of 2% to 10%. Therefore, initial risk stratification is important for proper management. We aimed...
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Sex Differences in the Effects of CDKAL1 Variants on Glycemic Control in Diabetic Patients: Findings from the Korean Genome and Epidemiology Study

Lee HA, Park H, Hong YS

Background: Using long-term data from the Korean Genome and Epidemiology Study, we defined poor glycemic control and investigated possible risk factors, including variants related to type 2 diabetes mellitus (T2DM)....
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The inhibitory effects of Rheum palmatum extract on the growth of oral streptococci and biofilm formation

Kim SY, Song Y, Lee HA, Na HS, Chung J

Objectives: Oral streptococci play a significant role in the development of dental caries. Among them, Streptococcus mutans and Streptococcus sobrinus are the principal causative agents of dental caries. Rheum palmatum...
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Association Between Gut Regulatory Hormones and Post-operative Weight Loss Following Gastrectomy in Patients With Gastric Cancer

Jung HK, Tae CH, Lee HA, Lee KE, Moon CM, Kim SE, Seoh JY, Lee JH

  • KMID: 2531186
  • J Neurogastroenterol Motil.
  • 2022 Jul;28(3):409-417.
  • doi: 10.5056/jnm21145
Background/Aims Post-operative weight loss in patients with gastric cancer lead to a poor quality of life and long-term survival. This study aims to evaluate the effects of gut regulatory hormones on...
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Therapeutic mechanisms and beneficial effects of non-antidiabetic drugs in chronic liver diseases

Lee HA, Chang Y, Sung PS, Yoon EL, Lee HW, Yoo JJ, Lee YS, An J, Song DS, Cho YY, Kim SU, Kim YJ

The global burden of chronic liver disease (CLD) is substantial. Due to the limited indication of and accessibility to antiviral therapy in viral hepatitis and lack of effective pharmacological treatment...
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Reappraisal of sepsis-3 and CLIF-SOFA as predictors of mortality in patients with cirrhosis and infection presenting to the emergency department: A multicenter study

Kim JH, Jun BG, Lee M, Lee HA, Kim TS, Heo JW, Moon DH, Kang SH, Suk KT, Kim MY, Kim YD, Cheon GJ, Baik SK, Kim DJ, Choi DH

Background/Aims: Sepsis-3 criteria and quick Sequential Organ Failure Assessment (qSOFA) have been advocated to be used in defining sepsis in the general population. We aimed to compare the Sepsis-3 criteria...
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A Case of Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma in Buccal Mucosa

Lee HA, Myung JK, Tae K

Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a lowgrade B-cell lymphoma that typically follows an indolent clinical course. It occurs in a variety of mucosal...
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Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer

Jun H, Lee J, Lee HA, Kim SE, Shim KN, Jung HK, Jung SA, Moon CM

Background/Aims: The relationship between fasting blood glucose (FBG) variability and colorectal cancer (CRC) remains ill-defined. This study aimed to evaluate the association of FBG variability with CRC risk in the...
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Increasing prevalence of fasting hyperglycemia in adolescents aged 10–18 years and its relationship with metabolic indicators: the Korea National Health and Nutrition Examination Study (KNHANES), 2007–2018

Yoo SE, Lee JH, Lee JW, Park HS, Lee HA, Kim HS

Purpose: Pediatric diabetes is a common health burden worldwide. This study aimed to investigate the prevalence of fasting hyperglycemia in Korean youth aged 10–18 years and to evaluate its association...
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Characterization of a Peptide Antibody Specific to the Adenylyl Cyclase-Associated Protein of Acanthamoeba castellanii

Kim MJ, Lee HA, Quan FS, Kong HH, Moon EK

Acanthamoeba keratitis (AK) is a rare infectious disease and accurate diagnosis has remained arduous as clinical manifestations of AK were similar to keratitis of viral, bacterial, or fungal origins. In...
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Adjustment for Multimorbidity in Estimations of the Burden of Diseases Using Korean NHIS Data

Shin Y, Choi EJ, Park B, Lee HA, Lee EK, Park H

The current multimorbidity correction method in the Global Burden of Disease studies assumes the independent occurrence of diseases. Those studies use Monte-Carlo simulations to adjust for the presence of multiple...
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