Korean J Hepatobiliary Pancreat Surg.  2012 Feb;16(1):1-6. 10.14701/kjhbps.2012.16.1.1.

Management and prevention of delayed gastric emptying after pancreaticoduodenectomy

• Kim YH

• KMID: 1434604
• DOI: http://doi.org/10.14701/kjhbps.2012.16.1.1

Abstract

Although technical advances have been made in pancreaticoduodenectomy, the incidence of delayed gastric emptying (DGE) is reported as being high. Postoperative DGE is not fatal, but often results in prolonging the length of patients' stay in hospital, increasing their medical expenses, and further lowering their quality of life. DGE is a complex process caused by disorder and incoordination of various factors in charge of gastric mobility, such as smooth muscle cells (myogenic), enteric neuron (hormonal), and autonomic nervous system (neural). DGE often occurs after operative maneuvers that cause the loss of organs responsible for gastric motility and emptying or kinetic muscular or neuromuscular ischemia. To prevent DGE, it is most important to develop and universalize a standardized surgical technique in a way to reduce factors that are considered to cause DGE after pancreaticoduodenectomy. Moreover, if it is suspected that DGE occurred after pancreaticoduodenectomy, a differential diagnosis from diseases with similar symptoms via an accurate diagnostic approach should be implemented.

Keyword

Pancreaticoduodenectomy; Delayed gastric emptying; Therapy; Prevention

MeSH Terms

Ataxia
Autonomic Nervous System
Diagnosis, Differential
Fees and Charges
Gastric Emptying
Incidence
Ischemia
Myocytes, Smooth Muscle
Neurons
Pancreaticoduodenectomy
Quality of Life

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