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Bone-only oligometastatic prostate cancer: can SABR improve outcomes? A single-center experience

Sánchez-Iglesias , Morillo-Macías V, Santafé-Jiménez A, Ferrer-Albiach C

Purpose: Ablative treatment of oligometastases has shown survival benefit with certain tumors, although these effects still are to be demonstrated in prostate cancer. Materials and Methods: We analysed the toxicity...
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Radiotherapy, volume reduction, and short-term surgical outcomes in the treatment of large myxoid liposarcomas

Lee LH, Tepper S, Owen G, Wang D, Lopez-Hisijos N, Colman MW, Gitelis S, Blank AT

Purpose: While tumor volume reduction following radiation has been documented in myxoid liposarcomas, it is unclear whether large tumors experience similar volume reduction to smaller tumors. Materials and Methods: MRI...
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Lazertinib: on the Way to Its Throne

Lee J, Hong MH, Cho BC

Lazertinib is an oral, irreversible, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that forms an irreversible covalent bond to the Cys797 residue in the ATP-binding site of...
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Current and future perspectives on CAR-T cell therapy for renal cell carcinoma: A comprehensive review

Kim TJ, Lee YH, Koo KC

In the clinical setting of renal cell carcinoma (RCC), immune reactions such as tumor-specific T cell responses can be spontaneous events or can be elicited by checkpoint inhibitors, cytokines, and...
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Treatment for relapsed acute promyelocytic leukemia: what is the best post-remission treatment?

Min GJ, Cho BS, Park SS, Park S, Jeon YW, Yahng SA, Shin SH, Yoon JH, Lee SE, Eom KS, Kim YJ, Lee S, Min CK, Cho SG, Lee JW, Kim HJ

Background Arsenic trioxide (ATO) is the standard treatment for relapsed acute promyelocytic leukemia (APL). However, consensus on post-remission therapies is still lacking. Methods We evaluated 52 patients who experienced relapse following initial treatment...
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Bispecific Antibody-Bound T Cells as a Novel Anticancer Immunotherapy

Cho J, Tae N, Ahn JH, Chang SY, Ko HJ, Kim DH

Chimeric antigen receptor T (CAR-T) cell therapy is one of the promising anticancer treatments. It shows a high overall response rate with complete response to blood cancer. However, there is...
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Bismuth-Based Quadruple Therapy versus MetronidazoleIntensified Triple Therapy as a First-Line Treatment for Clarithromycin-Resistant Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial

Seo SI, Lim H, Bang CS, Yang YJ, Baik GH, Lee SP, Jang HJ, Kae SH, Kim J, Kim HY, Shin WG

Background/Aims: Clarithromycin resistance is a main factor for treatment failure in the context of Helicobacter pylori infection. However, the treatment regimen for clarithromycin-resistant H. pylori infection has not yet been determined....
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Two-year clinical outcomes after discontinuation of long-term golimumab therapy in Korean patients with rheumatoid arthritis

Shin K, Kwon HM, Kim MJ, Yoon MJ, Chai HG, Kang SW, Park W, Park SH, Suh CH, Kim HA, Lee SG, Lee CK, Bae SC, Park YB, Song YW

Background/Aims: The aim of this study was to investigate long-term post-discontinuation outcomes in patients with rheumatoid arthritis (RA) who had been treated with tumor necrosis factor-α inhibitors (TNF-αi) which was...
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The effect of photodynamic therapy using Radachlorin on biofilm-forming multidrug-resistant bacteria

Seo CW, Kim YK, An JL, Kim JS, Kwon PS, Yu YB

Objectives: This study aimed to test the effect of photodynamic therapy (PDT) on the inhibition and removal of biofilms containing multidrug-resistant Acinetobacter baumannii. Methods: Using multidrug-resistant A. baumannii strains, an antibiotic...
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Alteration of Th1 and Th17 Inflammatory Cytokines in the Skin Lesions after Psoriasis Treatment

Park HJ, Chang HJ, Kim TG, Kwon MY, Lim CY, Ju HJ, Lee KH, Park CJ

  • KMID: 2532842
  • Korean J Dermatol.
  • 2022 Aug;60(7):409-413.
Background: Psoriasis is a T cell-mediated disorder. Appropriate treatment of psoriasis can result in a plethora of dynamic changes in the T cells and their cytokine production. Studies on the...
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Hormone Therapy and Risk of Breast Cancer: Where Are We Now?

Micha JP, Rettenmaier MA, Bohart RD, Goldstein BH

Several studies have examined the clinical benefits of hormone replacement therapy (HRT). However, because long-term use of HRT has been implicated as a risk factor for the development of breast...
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Korean Medication Algorithm Project for Bipolar Disorder 2022: Maintenance Therapy

Lee JG, Bahk WM, Woo YS, Jeong JH, Seo JS, Choo IH, Yang CM, Kim W, Shim SH, Jung MH, Jon DI, Park SY, Sohn I, Kim MD, Yoon BH

Objectives In this study, we investigated and organized the maintenance-treatment strategies for Bipolar I and II disorders outlined in The Korean Medication Algorithm Project for Bipolar disorder 2022 (KMAP-BP 2022). Methods...
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2021 Consensus Statements on the Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma From the Korean Renal Cancer Study Group (KRoCS)

Lee CH, Kang M, Kwak C, Kim SH, Kim JK, Park JY, Seo SI, Seo IY, Suh J, Song W, Song C, Yuk HD, Lee S, Lee HH, Chung J, Jeong CW, Jo JK, Choi CI, Choo SH, Han JH, Hwang EC, Kim M, Kim C, Choi SH, Hong SH

Purpose: The Korean Renal Cancer Study Group (KRoCS) provides consensus recommendations on the role of cytoreductive nephrectomy (CRN) in patients with metastatic renal cell carcinoma (mRCC). Materials and Methods: A group...
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Is Cytoreductive Nephrectomy Still Beneficial for Patients With Metastatic Renal Cell Carcinoma in the Contemporary Immunotherapy Era?

Choi JD, Cho JM, Yoo TK

Cytoreductive nephrectomy (CN) has long been the standard of care for patients with metastatic renal cell carcinoma (mRCC) since 2 clinical trials revealed its role during the cytokines era. With...
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Latent and Active Tuberculosis Infection in Patients with Inflammatory Bowel Disease

Jin BC, Moon HJ, Kim SW

Latent tuberculosis (TB) infections (LTBI) impose clinical challenges in terms of the diagnosis and treatment of inflammatory bowel disease (IBD), especially in TB-endemic areas. While steroids and biologics have become...
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Music and Sound-Based Intervention in Autism Spectrum Disorder: A Scoping Review

Shahrudin FA, Dzulkarnain AAA, Hanafi AM, Jamal FN, Basri NA, Sidek SN, Yusof HM, Khalid M

To map the evidence from the relevant studies regarding the use of music and sound-based intervention for autism spectrum disorder (ASD) using a scoping review study design. Scoping review was...
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Valproate Adjuvant Cognitive Behavioral Therapy in Panic Disorder Patients With Comorbid Bipolar Disorder: Case Series and Review of the Literature

Choi KY

Anxiety disorders are the most common comorbid psychiatric disorders in patients with bipolar disorder. Managing anxiety symptoms in comorbid conditions is challenging and has received little research interest. The findings...
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A Case of Voice Therapy for Long Standing Functional Aphonia

Kim BR, Woo JH

Functional aphonia is a disease in which normal vocal ability is suddenly lost. When voice therapy is started at an early stage, the prognosis is good. However, if the functional...
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A Case of Combination Therapy of IFN-β1b and Mitomycin-C on Recurred Ocular Surface Squamous Neoplasia

Lee JK, Son BK, Jin KH

Purpose: To report a case of combination therapy with interferon β1b (IFN-β1b) and mitomycin-C (MMC) for recurrent ocular surface squamous neoplasia (OSSN). Case summary: A 72-year-old female presented with a white...
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Pharmacotherapy in obesity: the current state and the near future

Cho YJ, Kim KK

Background: In Korea, the prevalence of obesity, morbid obesity with serious complications, and childhood obesity are rapidly increasing. To control the obesity pandemic, both prevention and treatment are essential strategic...
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