Korean J Med Mycol.
2013 Mar;18(1):16-19.
Recurrent Cerebral Infarction due to Rhino-Orbito-Cerebral Mucormycosis
- Affiliations
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- 1Department of Neurology, Kwandong University College of Medicine Myongji Hospital, Korea. nrkjy55@gmail.com
- 2Department of Pathology, Kwandong University College of Medicine Myongji Hospital, Korea.
Abstract
- Rhino-orbito-cerebral mucormycosis (ROCM) is caused by invasion of orbital and intracranial structures directly or through the blood vessels of fungi of the Order Mucorales. It is the most fulminant form of mucormycosis and can manifest brain abscess, cranial nerve palsies, thrombosis or aneurysm, as well as sinusitis, facial or nasal deformity. We report one ROCM case complicated by recurrent cerebral infarctions after involvement of cavernous sinus and meningeal inflammation, despite treatment with surgical debridement and high dose intravenous amphotericin B.
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