Korean J Dermatol.  2013 Aug;51(8):639-642.

Necrobiosis Lipoidica Over Surgical Scar in a Patient without Diabetes Mellitus

Affiliations
  • 1Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea. yuhjoon@hanyang.ac.kr

Abstract

Necrobiosis lipoidica (NL) is a chronic granulomatous skin disease typified by indurated plaques on the shin. Although this condition is strongly associated with diabetes mellitus, its etiology and pathogenesis remains unknown. Localization of NL to the lower extremities suggests that local injury may be a contributing factor to the disease. A healthy 38-year-old man presented with localized erythematous to yellowish plaques on his right thigh that developed over several years. The lesion developed in the scar where suture had been done for laceration repair 25 years ago. A biopsy specimen showed degenerated collagen with surrounding palisading granulomas. Numerous lymphocytes and multinucleated giant cells were infiltrated throughout the reticular dermis. Plasma cells aggregation was found at the dermal subcutaneous junction.

Keyword

Diabetes mellitus; Necrobiosis lipoidica; Scar

MeSH Terms

Biopsy
Cicatrix
Collagen
Dermis
Diabetes Mellitus
Giant Cells
Granuloma
Humans
Lacerations
Lower Extremity
Lymphocytes
Necrobiosis Lipoidica
Necrobiotic Disorders
Plasma Cells
Skin Diseases
Sutures
Thigh
Collagen
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