Korean J Gastroenterol.
2003 Jun;41(6):504-508.
A Case of Ischemic Colitis Associated with Antiphospholipid Syndrome
- Affiliations
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- 1Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. sjm5675@amc.seoul.kr
- 2Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
- 3Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Abstract
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There are various causes of ischemic colitis. It can be largely divided into occlusive and non-occlusive causes: thrombus formation in the superior or inferior mesenteric arteies secondary to atherosclerotic vascular lesion is one of the most frequent occlusive causes; hypotensive state due to causes such as hemorrhage is one of common examples of non-occlusive causes. Antiphospholipid antibody is associated with numerous thromboembolic phenomena. We report a case of elderly male who presented with ischemic colitis and was diagnosed as having antiphospholipid syndrome later. He was positive for lupus anticoagulant, showed mesenteric venous thrombosis on abdominal CT, and experienced acalculous cholecystitis during the hospital course. The patient's clinical, laboratory, and pathologic findings are consistent with ischemic colitis associated with antiphospholipid syndrome.