J Prev Med Public Health.  2011 Sep;44(5):218-225. 10.3961/jpmph.2011.44.5.218.

Relationship Between Blood Mercury Concentration and Waist-to-Hip Ratio in Elderly Korean Individuals Living in Coastal Areas

• You CH
• Kim BG
• Kim JM
• Yu SD
• Kim YM
• Kim RB
• Hong YS

• KMID: 1022162
• DOI: http://doi.org/10.3961/jpmph.2011.44.5.218

Abstract

OBJECTIVES
This study investigated the relationship between the blood mercury concentration and cardiovascular risk factors in elderly Korean individuals living in coastal areas.
METHODS
The sample consisted of 477 adults (164 males, 313 females) aged 40 to 65 years who visited a Busan health promotion center from June to September in 2009. The relationship between blood mercury concentration and cardiovascular risk factors including metabolic syndrome, cholesterol profiles, blood pressure, body mass index (BMI), waist circumference and waist-to-hip ratio (WHR), was investigated. Variables related to blood mercury concentration were further evaluated using multiple regression analysis.
RESULTS
The blood mercury concentration of the study population was 7.99 (range, 7.60 to 8.40) microg/L. In males, the blood mercury concentration was 9.74 (8.92 to 10.63) microg/L, which was significantly higher than that in females (7.21, [6.80 to 7.64] microg/L). The blood mercury concentration of the study population was related to several cardiovascular risk factors including low-density lipoprotein (LDL) cholesterol (p=0.044), high-density lipoprotein (HDL) cholesterol (p=0.034), BMI (p = 0.006), waist circumference (p = 0.031), and WHR (p < 0.001). In males, the blood mercury concentration was significantly correlated with WHR in the multiple regression analysis.
CONCLUSIONS
In males, the blood mercury concentration was related to waist-to-hip ratio, which is a central obesity index and cardiovascular risk factor. Our finding suggests that cardiovascular disease risk in males was increased by mercury exposure via an obesity-related mechanism.

Keyword

Cardiovascular risk factor; Mercury; Obesity; Waist-to-hip ratio

MeSH Terms

Adult
Aged
Asian Continental Ancestry Group
Body Mass Index
Cardiovascular Diseases/blood/etiology
Cholesterol, HDL/blood
Cholesterol, LDL/blood
Female
Humans
Interviews as Topic
Male
Mercury/*blood
Middle Aged
Questionnaires
Regression Analysis
Republic of Korea
Risk Factors
Waist Circumference
*Waist-Hip Ratio