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Localization of cytoskeletal proteins in Cryptosporidium parvum using double immunogold labeling

Yu JR, Lee SH

Actin and some actin binding proteins such as tropomyosin, -actinin and troponin T were localized by simultaneous double immunogold labeling in several developmental stages of Cryptosporidium parvum. All of the...
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Clonorchis sinensis tropomyosin: cloning and sequence of partial cDNA amplified by PCR

Hong SJ

C. sinensis total RNA was containing large amount of 18S rRNA but little 28S rRNA. The size of the double-stranded cDNA synthesized from poly (A)+ mRNA was 0.4-4.2 kb long...
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Distribution of actin and tropomyosin in Cryptosporidium muris

Yu JR

Actin and tropomyosin of Cryptosporidium muris were localized by immunogold labeling. Two kinds of antibodies for actin labeling were used. The polyclonal antibody to skeletal muscle (chicken back muscle)...
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A Family of Congenital Fiber Type Disproportion with Mutation in Tropomyosin 3 (TPM3) Gene Presenting as Altered Mentality with Respiratory Distress

Namgung DW, Hong JM, Lee JH, Park HJ, Choi YC

Congenital fiber type disproportion (CFTD) has been related with mutations in ACTA1, SEPN1, RYR1 and tropomyosin 3 (TPM3) genes. Particularly, TPM3 mutation was identified as one of the most frequent...
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Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin?

Wong L, Huang CH, Lee BW

Crustacean shellfish allergy is an important cause of food allergy and anaphylaxis in Asia. The major allergen in shellfish allergy is tropomyosin, a pan-allergen that is also found in house...
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Cap Myopathy With a Heterozygous TPM3 Missense Mutation

Jung Y, Park YE, Shin JH, Lee CH, Kim DS

Cap myopathy is pathologically characterized by cap structures comprising well-demarcated areas under the sarcolemma and containing deranged myofibrils and scattered Z-disks. Clinically it presents with slowly progressive muscle weakness, myopathic...
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Localization of cytoskeletal proteins in Pneumocystis carinii by immuno-electron microscopy

Yu JR, Pyon JK, Seo M, Jung BS, Cho SR, Lee SH, Hong ST

Pneumocystis carinii causes serious pulmonary infection in immunosuppressed patients. This study was undertaken to observe the cytoskeletal proteins of P. carinii by immuno-electron microscopy. P. carinii infection was experimentally...
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Identification of Oocyte-Specific Diva-Associated Proteins using Mass Spectrometry

Yoon SJ, Kim JW, Choi KH, Lee SH, Lee KA

  • KMID: 2085182
  • Korean J Fertil Steril.
  • 2006 Sep;33(3):189-198.
OBJECTIVE: We previously described that Diva is highly expressed in matured metaphase II (MII) oocytes compared to immature germinal vesicle (GV) oocytes in mouse.1 We report here that the expression...
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First Korean Family with a Mutation in TPM2 Associated with Sheldon-Hall Syndrome

Ko JM, Choi IH, Baek GH, Kim KW

Sheldon-Hall syndrome (SHS) is a rare autosomal dominant, inherited arthrogryposis syndrome characterized by multiple congenital contractures of the distal limbs. To date, four genes that encode the skeletal muscle fiber...
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Increased Levels of C1q in the Prefrontal Cortex of Adult Offspring after Maternal Immune Activation: Prevention by 7,8-Dihydroxyflavone

Han M, Zhang JC, Hashimoto

OBJECTIVE: Prenatal infection is implicated in the etiology of schizophrenia. The objective of this paper is to study the role of complement protein C1q in the psychosis of adult offspring...
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Probing Regulatory Proteins for Vascular Contraction by Deoxyribonucleic Acid Microarray

Kim JI, Kim IK

BACKGROUND AND OBJECTIVES: The heat-shock response modulates contractility of vascular smooth muscles. With complementary deoxyribonucleic acid microarray, we tried to identify the novel genes that are involved in the regulation...
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Effect of Environmental Enrichment on Cognitive Impairment-induced by Ethanol Exposure in Adolescent Rat

Kim YJ, Park JM, Song MK, Seong HH, Kim YJ

PURPOSE: Adolescents who experienced the alcohol consumption have gradually increased. Adolescence is a critical period of the neural plasticity in the brain. Neural plasticity is mediated by neurotrophins and has...
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Early Time Course of Immunopathologic Changes in Coronary Arteries of Heterotopically Transplanted Mouse Heart

Lee JR, Lim HG, Suh JW

  • KMID: 2288945
  • Korean J Thorac Cardiovasc Surg.
  • 1998 Dec;31(12):1119-1126.
BACKGROUND: In this study, we investigated the early time course of expression of the major histocompatibility (MHC) antigens, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), interleukin-6 and the...
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Evaluation of Diagnostic Efficiency of Troponin T Measurement in Acute Myocardial Infarction and Ischemic Heart Disease

Park MJ, Kim HT, Park SY, Lee KS

  • KMID: 2089443
  • Korean J Clin Pathol.
  • 1997 Aug;17(4):560-568.
BACKGROUND: Troponin T(TnT), a 37 kDa polypeptide subunit of contractile protein, is part of the troponin complect in striated muscle, where it binds to tropomyosin. TnT is not usually found...
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Differential Clinical Significance of Neurotrophin-3 Expression according to MYCN Amplification and TrkC Expression in Neuroblastoma

Seo E, Kim JS, Ma YE, Cho HW, Ju HY, Lee SH, Lee JW, Yoo KH, Sung KW, Koo HH

BACKGROUND: Neurotrophin-3 (NT-3), a member of the NT family, has only been considered an ancillary compound that provides anti-apoptotic benefits by inactivating tropomyosin receptor kinase C (TrkC)-induced apoptotic signals. However,...
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Restoration of Cdk5, TrkB and Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor Proteins after Chronic Methylphenidate Treatment in Spontaneous Hypertensive Rats, a Model for Attention-Deficit Hyperactivity Disorder

Kim Y, Jeon S, Jeong HJ, Lee SM, Peña ID, Kim HJ, Han DH, Kim BN, Cheong JH

OBJECTIVE: Synaptic vesicle mobilization and neurite outgrowth regulation molecules were examined in modulation of effects of methylphenidate (MPH) in Spontaneous Hypertensive Rats (SHRs), a model for attention-deficit hyperactivity disorder (ADHD). METHODS:...
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cDNA Microarray Analysis of Differential Gene Expression in Gastric Cancer Cells Sensitive and Resistant to 5-Fluorouracil and Cisplatin

Ahn MJ, Yoo YD, Lee KH, Ahn JI, Yu DH, Lee HS, Oh HS, Choi JH, Lee YS

  • KMID: 1743356
  • Cancer Res Treat.
  • 2005 Feb;37(1):54-62.
PURPOSE: Gastric cancer is one of the most prevalent cancers worldwide. 5-fluorouracil (5-FU) and cisplatin are the most commonly used drugs for the treatment of gastric cancer. However, a significant...
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Gene Expression Profile of Volume-Overloaded Human Ventricular Myocardium Prior to Developing Heart Failure

Yang CH, Lee SH, Park TH, Cha KS, Kim MH, Kim YD, Woo JS, Roh MS, Hwang TH

BACKGROUND AND OBJECTIVES: Left ventricle burdened by longstanding volume-overload, undergoes various structural and functional alterations. Accordingly, the expressions of multiple classes of genes are likely to be altered. However, the...
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Specific IgE determination to shrimp (Metapenaeus joyneri) and identification of its allergen

Yoon SH, Choi JH, Suh YJ, Suh CH, Nahm DH, Kim YK, Min KU, Park HS

  • KMID: 1620617
  • Korean J Med.
  • 2003 Aug;65(2):231-238.
BACKGROUND: Shrimp is one of the major causative crustacean food allergen. An investigation has been reported that tropomyosin belonged to muscle protein is a major allergen within shrimp. But there...
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Proteomic analyses of cervical cancer tissues by two-dimensional gel electrophoresis and mass spectrometry

Lee SH, Bae SM, Kim OK, Kim HJ, Park EK, Lee HN, Kim YW, Ro DY, Lee JM, Namkoong S, Cho YL, Nam GH, Han BD, Kim YW, Kim CK, Ahn WS

  • KMID: 2272627
  • Korean J Obstet Gynecol.
  • 2005 Jul;48(7):1686-1697.
OBJECTIVE: Comparison of protein expressions by two-dimensional gel electrophoresis (2-DE) in normal cervix and squamous cell carcinoma tissues in Korean women. METHODS: Normal cervix and squamous cell carcinoma tissues were solubilized...
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