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PrimateDB: Development of Primate Genome DB and Web Service

Woo T, Shin G, Kang T, Kim B, Seo J, Kim SS, Kim CB

  • KMID: 1572638
  • Genomics Inform.
  • 2005 Jun;3(2):73-76.
The comparative analysis of the human and primate genomes including the chimpanzee can reveal unique types of information impossible to obtain from comparing the human genome with the genomes of...
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Establishment of a Research and Assessment System Using High Quality Non-Human Primates

Hyun BH, Kang BC, Kim CK, Kim HS, Suh JG, Cho F

At present, eight non-human primate research facilities exist in Korea to examine the validity and safety of new bio-products, and to generate model animal systems using primates of low health...
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Experimental Pancreas Islet Isolation in Non- Human Primate

Kim SC, Han DJ, Hering BJ

  • KMID: 2198970
  • J Korean Soc Transplant.
  • 2001 Dec;15(2):142-146.
Transplantation of the pancreas islet cell has been demonstrated to be able to cure for type I diabetes. It can offer not only discontinuing of insulin but also preventing of...
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Genomic Features of Retroelements and Implications for Human Disease

Kim HS

  • KMID: 2284672
  • Genomics Inform.
  • 2005 Dec;3(4):133-141.
Most of the endogenous retroviral genes integrated into the primate genome after the split of New World monkeys in the Oligocene era, approximately 33 million years ago. Because they can...
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Periodic Explosive Expansion of Human Retroelements Associated with the Evolution of the Hominoid Primate

Kim TM, Hong SJ, Rhyu MG

Five retroelement families, L1 and L2 (long interspersed nuclear element, LINE), Alu and MIR (short interspersed nuclear element, SINE), and LTR (long terminal repeat), comprise almost half of the human...
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Structural Variation of Alu Element and Human Disease

Kim S, Cho CS, Han K, Lee J

Transposable elements are one of major sources to cause genomic instability through various mechanisms including de novo insertion, insertion-mediated genomic deletion, and recombination-associated genomic deletion. Among them is Alu element...
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Menstruation and Sleep

Park DH

  • KMID: 2317377
  • Sleep Med Psychophysiol.
  • 2002 Dec;9(2):81-85.
There are several factors which are more likely to have sleep disorders in fertile women with menstruation than adult men. Menstrual cycle plays an important role in them. We describe...
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Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling

Park J, Seo J, Won J, Yeo HG, Ahn YJ, Kim K, Jin YB, Koo BS, Lim KS, Jeong KJ, Kang P, Lee HY, Baek SH, Jeon CY, Hong JJ, Huh JW, Kim YH, Park SJ, Kim SU, Lee DS, Lee SR, Lee Y

Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is...
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Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR

Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and...
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Acute gastrointestinal dilation in laboratory rhesus monkeys in the Korea National Primate Research Center

Kim KM, Lee SR, Chang KS, Lee YH, Kim SW, Jung KJ, Lee Y, Kim D, Chang KT

Acute gastrointestinal dilation is a medical condition in which the stomach and intestine become overstretched by excessive gas content. In laboratory monkeys, cases of bloating involving gastrointestinal dilation are rarely...
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Evaluation of fecal microbiomes associated with obesity in captive cynomolgus monkeys (Macaca fascicularis)

Koo BS, Hwang EH, Kim G, Oh H, Son Y, Lee D, Lim KS, Kang P, Lee S, Lee HY, Jeong KJ, Lee Y, Baek SH, Jeon CY, Park SJ, Kim YH, Huh JW, Jin YB, Kim SU, Lee SR, Hong JJ

Microorganisms play important roles in obesity; however, the role of the gut microbiomes in obesity is controversial because of the inconsistent findings. This study investigated the gut microbiome communities in...
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Decoding Saccadic Directions Using Epidural ECoG in Non-Human Primates

Lee J, Choi H, Lee S, Cho BH, Ahn KH, Kim IY, Lee KM, Jang DP

A brain-computer interface (BCI) can be used to restore some communication as an alternative interface for patients suffering from locked-in syndrome. However, most BCI systems are based on SSVEP, P300,...
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Three-axis Modification of Coordinates Enables Accurate Stereotactic Targeting in Non-human Primate Brains of Different Sizes

Kim HS, Kang GH, Song H, Kim RG, Park JY, Hwang JH, Kim HI

The brain grows with age in non-human primates (NHPs). Therefore, atlas-based stereotactic coordinates cannot be used directly to target subcortical structures if the size of the animal's brain differs from...
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Use of Nonhuman Primates for the Development of Bioengineered Female Reproductive Organs

Yun JW, Kim YY, Ahn JH, Kang BC, Ku SY

Nonhuman primates (NHPs) have been widely used in reproductive biology, neuroscience, and drug development since a number of primate species are phylogenetically close to humans. In this review, we summarize...
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Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys

Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR

The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in...
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Cryptosporidium spp., Giardia intestinalis, and Enterocytozoon bieneusi in Captive Non-Human Primates in Qinling Mountains

Du SZ, Zhao GH, Shao JF, Fang YQ, Tian GR, Zhang LX, Wang RJ, Wang HY, Qi M, Yu SK

Non-human primates (NHPs) are confirmed as reservoirs of Cryptosporidium spp., Giardia intestinalis, and Enterocytozoon bieneusi. In this study, 197 fresh fecal samples from 8 NHP species in Qinling Mountains, northwestern...
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Characteristics of Animal Shoulder Models for Rotator Cuff Experiments

Kim MC, Kim MS

Animal shoulder models are important in the investigation of the natural history of various pathologic conditions and for evaluation of the effectiveness of different treatments and biomaterials. The characteristics of...
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Temporal Pole Projections to the Ventral Shell Striatal Subterritory in the Primate

Jung Y

  • KMID: 1610760
  • Korean J Anat.
  • 2003 Aug;36(4):265-270.
Paralimbic association area in the temporal pole is situated between sensory association areas and the limbic regions and has direct connections with these areas and the ventral striatum. Corticostriatal connections...
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Zika Virus Infection

Yoon HJ, Yeom JS

Zika virus was first isolated in from nonhuman primate in 1947. It is in the genus Flavivirus, closely related to other flavivirus like Dengue, West Nile, Yellow fever and Japanese...
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Transposable Elements: No More 'Junk DNA'

Kim YJ, Lee J, Han K

Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes. Many studies about...
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