Korean J Med.  2016 Aug;91(1):5-11. 10.3904/kjm.2016.91.1.5.

Zika Virus Infection

Affiliations
  • 1Division of Infectious Diseases, Seoul Metropolitan Government Seobuk Hospital, Seoul, Korea.
  • 2Division of Infectious Diseases, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. jsyeom@skku.edu

Abstract

Zika virus was first isolated in from nonhuman primate in 1947. It is in the genus Flavivirus, closely related to other flavivirus like Dengue, West Nile, Yellow fever and Japanese encephalitis virus. Since 2007 epidemic in Yap island, zika virus infections had spread to the countries in Micronesia and South Pacific. In 2015, Zika virus outbreak occurred in Brazil and now more than 40 countries in American continents reported autochthonous infection. The virus is transmitted mainly by Ae. aegypti mosquito with many other Aedes mosquito species known as vector. Recently, Zika virus infection is known to cause severe neurological complications and congenital malformation. In this paper, we will review current knowledge on Zika virus history, biology, clinical characteristics and preventive method.

Keyword

Zika virus; Flavivirus; Microcephaly; Aedes

MeSH Terms

Aedes
Biology
Brazil
Culicidae
Dengue
Encephalitis Virus, Japanese
Flavivirus
Methods
Microcephaly
Micronesia
Primates
Yellow Fever
Zika Virus Infection*
Zika Virus*
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