Lab Anim Res.  2010 Dec;26(4):449-457. 10.5625/lar.2010.26.4.449.

Establishment of a Research and Assessment System Using High Quality Non-Human Primates

• Hyun BH
• Kang BC
• Kim CK
• Kim HS
• Suh JG
• Cho F

• KMID: 2114716
• DOI: http://doi.org/10.5625/lar.2010.26.4.449

Abstract

At present, eight non-human primate research facilities exist in Korea to examine the validity and safety of new bio-products, and to generate model animal systems using primates of low health status (low quality primates). However specific-pathogen free (SPF) primates (high quality primates) are the preferred choice for emerging disease studies and for numerous other research areas, including cell/gene therapy, stem cell research, regenerative studies, and brain science. Although international primate centers in developed countries have utilized high quality primate resources for many years, there has been little or no collaboration with less developed countries on primate research. Due to this, the establishment of a high quality primate research capacity is a core priority for the advancement of the biomedical research field in less developed countries. In this study, we investigated the demand for, and opportunities to support the development of this research capability.

Keyword

Non-human primates; high quality primate; low quality primate; SPF

MeSH Terms

Animals
Brain
Cooperative Behavior
Developed Countries
Developing Countries
Korea
Primates
Stem Cell Research

Figure

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  Figure 1. Annual number of primates imported into USA, Japan and Korea.

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  Figure 2. Suitability of low and high quality primates for biomedical research.

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  Figure 3. Fields of users on non-human primates using survey in Korea.

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  Figure 4. Preferred approach for addressing international competition from existing high quality primate research centers.

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  Figure 5. Critical roles for national demand and using with non-human primates.

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  Figure 6. Priorities to be met by a high quality primate research system.

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  Figure 7. Process for deriving SPF accredited macaques.

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  Figure 8. Design concept for high quality primate research center.

Reference

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