- Sinapic Acid Attenuates the Neuroinflammatory Response by Targeting AKT and MAPK in LPS-Activated Microglial Models
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Huang T, Zhao D, Lee S, Keum G, Yang HO
- KMID: 2541786
- Biomol Ther.
- 2023 May;31(3):276-284.
- doi: 10.4062/biomolther.2022.092
Sinapic acid (SA) is a phenolic acid that is widely distributed in fruits and vegetables, which has various bioactivities, such as antidiabetic, anticancer and anti-inflammatory functions. Over-activated microglial is involved... -
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- Neuroprotective Effect of Astersaponin I against Parkinson’s Disease through Autophagy Induction
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Zhang L, Park JY, Zhao D, Kwon HC, Yang HO
- KMID: 2522249
- Biomol Ther.
- 2021 Nov;29(6):615-629.
- doi: 10.4062/biomolther.2021.004
An active compound, triterpene saponin, astersaponin I (AKNS-2) was isolated from Aster koraiensis Nakai (AKNS) and the autophagy activation and neuroprotective effect was investigated on in vitro and in vivo... -
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- Osteonecrosis of the Femoral Head: an Updated Review of ARCO on Pathogenesis, Staging and Treatment
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Hines JT, Jo WL, Cui Q, Mont MA, Koo KH, Cheng EY, Goodman SB, Ha YC, Hernigou P, Jones LC, Kim SY, Sakai T, Sugano N, Yamamoto T, Lee MS, Zhao D, Drescher W, Kim TY, Lee YK, Yoon BH, Baek SH, Ando W, Kim HS, Park JW
- KMID: 2516767
- J Korean Med Sci.
- 2021 Jun;36(24):e177.
- doi: 10.3346/jkms.2021.36.e177
Non-traumatic osteonecrosis of the femoral head (ONFH) usually affects adults younger than 50 years and frequently leads to femoral head collapse and subsequent arthritis of the hip. It is becoming more... -
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- ARCO Consensus on the Pathogenesis of Non-traumatic Osteonecrosis of the Femoral Head
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Cui Q, Jo WL, Koo KH, Cheng EY, Drescher W, Goodman SB, Ha YC, Hernigou P, Jones LC, Kim SY, Lee KS, Lee MS, Lee YJ, Mont MA, Sugano N, Taliaferro J, Yamamoto T, Zhao D
- KMID: 2513706
- J Korean Med Sci.
- 2021 Mar;36(10):e65.
- doi: 10.3346/jkms.2021.36.e65
Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised... -
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- A Preoperative Nomogram for Predicting Chemoresistance to Neoadjuvant Chemotherapy in Patients with Locally Advanced Cervical Squamous Carcinoma Treated with Radical Hysterectomy
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Ou Z, Zhao D, Li B, Wang Y, Liu S, Zhang Y
- KMID: 2510665
- Cancer Res Treat.
- 2021 Jan;53(1):233-242.
- doi: 10.4143/crt.2020.159
Purpose This study aimed to investigate the factors associated with chemoresistance to neoadjuvant chemotherapy (NACT) followed by radical hysterectomy (RH) and construct a nomogram to predict the chemoresistance in patients... -
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- Portal pressure gradient and serum albumin: A simple combined parameter associated with the appearance of ascites in decompensated cirrhosis treated with transjugular intrahepatic portosystemic shunt
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Zhao D, Zhang G, Wang M, Zhang C, Li J
- KMID: 2451925
- Clin Mol Hepatol.
- 2019 Jun;25(2):210-217.
- doi: 10.3350/cmh.2018.0083
BACKGROUND/AIMS: In recent years, greater assessment accuracy after transjugular intrahepatic portosystemic shunt (TIPS) to ascertain prognosis has become important in decompensated cirrhosis due to portal hypertension. The aim of this... -
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- Anti-neuroinflammatory Effects of 12-Dehydrogingerdione in LPS-Activated Microglia through Inhibiting Akt/IKK/NF-κB Pathway and Activating Nrf-2/HO-1 Pathway
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Zhao D, Gu MY, Xu JL, Zhang LJ, Ryu SY, Yang HO
- KMID: 2432072
- Biomol Ther.
- 2019 Jan;27(1):92-100.
- doi: 10.4062/biomolther.2018.104
Ginger, one of worldwide consumed dietary spice, is not only famous as food supplements, but also believed to exert a variety of remarkable pharmacological activity as herbal remedies. In this... -
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- Identification of determinants that mediate binding between Tembusu virus and the cellular receptor heat shock protein A9
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Zhao D, Liu Q, Huang X, Wang H, Han K, Yang J, Bi K, Liu Y, Zhang L, Li Y
- KMID: 2417568
- J Vet Sci.
- 2018 Jul;19(4):528-535.
- doi: 10.4142/jvs.2018.19.4.528
Heat shock protein A9 (HSPA9), a member of the heat shock protein family, is a putative receptor for Tembusu virus (TMUV). By using Western blot and co-immunoprecipitation assays, E protein... -
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- The Benefits of Indirect Exposure to Trauma: The Relationships among Vicarious Posttraumatic Growth, Social Support, and Resilience in Ambulance Personnel in China
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Kang X, Fang Y, Li S, Liu Y, Zhao D, Feng X, Wang Y, Li P
- KMID: 2462784
- Psychiatry Investig.
- 2018 May;15(5):452-459.
- doi: 10.30773/pi.2017.11.08.1
OBJECTIVE: Ambulance personnel who witness trauma experienced by patients have been reported to experience positive changes, known as vicarious posttraumatic growth (VPTG). We examined VPTG and its relationship with social... -
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- Population-Stratified Analysis of Bone Mineral Density Distribution in Cervical and Lumbar Vertebrae of Chinese from Quantitative Computed Tomography
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Zhang Y, Zhou Z, Wu C, Zhao D, Wang C, Cheng X, Cai W, Wang L, Duanmu Y, Zhang C, Tian W
- KMID: 2458050
- Korean J Radiol.
- 2016 Oct;17(5):581-589.
- doi: 10.3348/kjr.2016.17.5.581
OBJECTIVE: To investigate the bone mineral density (BMD) of cervical vertebrae in a population-stratified manner and correlate with that of the lumbar vertebrae. MATERIALS AND METHODS: Five hundred and ninety-eight healthy... -
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- Activation of the wnt/β-Catenin Signaling Pathway in Polymyositis, Dermatomyositis and Duchenne Muscular Dystrophy
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Liu F, Liang Z, Xu J, Li W, Zhao D, Zhao Y, Yan C
- KMID: 2354124
- J Clin Neurol.
- 2016 Jul;12(3):351-360.
- doi: 10.3988/jcn.2016.12.3.351
BACKGROUND AND PURPOSE: The wnt/β-catenin signaling pathway plays a critical role in embryonic development and adult-tissue homeostasis. Recent investigations implicate the importance of wnt/β-catenin signaling in normal wound healing and... -
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- Hypertriglyceridemia and Cardiovascular Diseases: Revisited
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Han SH, Nicholls S, Sakuma I, Zhao D, Koh KK
- KMID: 2344463
- Korean Circ J.
- 2016 Mar;46(2):135-144.
- doi: 10.4070/kcj.2016.46.2.135
Residual cardiovascular risk and failure of high density lipoprotein cholesterol raising treatment have refocused interest on targeting hypertriglyceridemia. Hypertriglyceridemia, triglyceride-rich lipoproteins, and remnant cholesterol have demonstrated to be important risk... -
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- Relapse of Clubfoot after Treatment with the Ponseti Method and the Function of the Foot Abduction Orthosis
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Zhao D, Liu J, Zhao L, Wu Z
- KMID: 1794703
- Clin Orthop Surg.
- 2014 Sep;6(3):245-252.
- doi: 10.4055/cios.2014.6.3.245
Ponseti clubfoot treatment has become more popular during the last decade because of its high initial correction rate. But the most common problem affecting the long-term successful outcome is relapse... -
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