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A Case of Benign Atrophic Papulosis in a Young Male

Lu L, Lin B, Dai R, Fan X, Yu Y, Qi Y, Zhu X, Zhou P

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Inhibition of Store-Operated Calcium Entry Protects Endothelial Progenitor Cells from Hâ‚‚Oâ‚‚-Induced Apoptosis

Wang YW, Zhang JH, Yu Y, Yu J, Huang L

Store-operated calcium entry (SOCE), a major mode of extracellular calcium entry, plays roles in a variety of cell activities. Accumulating evidence indicates that the intracellular calcium ion concentration and calcium...
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CT Fractional Flow Reserve for the Diagnosis of Myocardial Bridging-Related Ischemia: A Study Using Dynamic CT Myocardial Perfusion Imaging as a Reference Standard

Yu Y, Yu L, Dai X, Zhang J

Objective: To investigate the diagnostic performance of CT fractional flow reserve (CT-FFR) for myocardial bridging-related ischemia using dynamic CT myocardial perfusion imaging (CT-MPI) as a reference standard. Materials and Methods: Dynamic...
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The Role of Pentraxin 3 in Aspergillosis: Reality and Prospects

Kang Y, Yu Y, Lu L

Pentraxin 3 (PTX3) is a soluble pattern recognition receptor (PRR), which is produced by several kinds of cells, such as neutrophils, dendritic cells, macrophages, and epithelial cells. PTX3 is known to play...
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Lipids, Anthropometric Measures, Smoking and Physical Activity Mediate the Causal Pathway From Education to Breast Cancer in Women: A Mendelian Randomization Study

Li H, Hou L, Yu Y, Sun X, Liu X, Yu Y, Wu S, He Y, Wu Y, He L, Xue F

Purpose: We aimed to investigate whether obtaining a higher level of education was causally associated with lower breast cancer risk and to identify the causal mechanism linking them. Methods: The main...
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Practical considerations for the study of the oral microbiome

Yu Y, Lee Sy, Na HS

In the oral cavity, complex microbial community is shaped by various host and environmental factors. Extensive literature describing the oral microbiome in the context of oral health and disease is...
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Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice

Guo Q, Shen Z, Yu H, Lu G, Yu Y, Liu X, Zheng P

Acetaminophen (APAP) overdose is one of the most common causes of acute liver failure. The study aimed to investigate the protective effect of carnosic acid (CA) on APAP-induced acute hepatotoxicity...
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Massive Hemoptysis due to Endotracheal Hemangioma: A Case Report and Literature Review

Yu Y, Lee S, An J, Lee J, Kim J, Lee Y, Jung E, Song S, Kim H, Kim S

Tracheal hemangioma is a rare benign vascular tumor in adults. We reported a case of massive hemoptysis caused by a cavernous hemangioma in a 75-year-old man. This is the first...
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Successful Infliximab Therapy in a Patient with Refractory Takayasu's Arteritis

An J, Yu Y, Lee S, Lee H, Choi BY

Takayasu's arteritis (TA), a granulomatous vasculitis, affects the aorta and its major branches. Glucocorticoids are an effective treatment for patients with active TA, but some patients fail to achieve or...
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Experience of Work-Study Balance among Clinical Nurses in a Nursing Doctoral Program: A Qualitative Study

Noh S, Yu Y, Choi S

Purpose: The purpose of this study was to explore the experience of work-study balance among clinical nurses in a nursing doctoral program. Methods: The participants were nine clinical nurses in a...
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Acute Kidney Injury Following Chemical Burns Caused by Hexavalent Chromium

Lee Y, Yu Y, An JN, Lee JP, Lim CS, Oh YK

The metal chromium is widely used in industry. Hexavalent chromium is a strong oxidizing agent, and exposure to some hexavalent compounds can cause serious problems, such as skin ulcers, acute...
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Trimming conditions for DADA2 analysis in QIIME2 platform

Lee SY, Yu Y, Chung J, Na HS

Accurate identification of microbes facilitates the prediction, prevention, and treatment of human diseases. To increase the accuracy of microbiome data analysis, a long region of the 16S rRNA is commonly...
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The Physiological Functions and Polymorphisms of Type II Deiodinase

Deng Y, Han Y, Gao S, Dong W, Yu Y

Type II deiodinase (DIO2) is thought to provide triiodothyronine (T3) to the nucleus to meet intracellular needs by deiodinating the prohormone thyroxine. DIO2 is expressed widely in many tissues and...
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Xylazole inhibits NO-cGMP pathway in fetal rat nerve cells

Wang X, Wu Y, Liu L, Bai H, Zhang Z, Zhao M, Ma T, Song X, Jia L, Lv L, Yu Y, Xu X, Chen H, Gao L

Background: Xylazole (Xyl) is a veterinary anesthetic that is structurally and functionally similar to xylazine. However, the effects of Xyl in vitro remain unknown. Objectives: This study aimed to investigate the...
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The unique changes of lung microbiome in chronic lung allograft dysfunction

Yeo HJ, Cho WH, Kim D, Kim YH, Yu Y

Background: Both unique bacterial populations and longitudinal changes in the lung microbiome may play a critical role in the development of chronic lung allograft dysfunction (CLAD). Methods: We evaluated the difference...
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Injectable Poloxamer Hydrogel Formulations for Intratympanic Delivery of Dexamethasone

Le TP, Yu Y, Cho IS, Suh EY, Kwon HC, Shin SA, Park YH, Huh KM

Background: In this study, we prepared and evaluated an injectable poloxamer (P407) hydrogel formulation for intratympanic (IT) delivery of dexamethasone (DEX). Methods: DEX-loaded P407 hydrogels were characterized in terms of thermogelation,...
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Traumatic Events and Factors Affecting Post-traumatic Growth of Nurses in General Hospitals

Kim H, Kim E, Yu Y

Purpose: The purpose of this study was to investigate the factors that affect post-traumatic growth of general hospital nurses after they experience traumatic events. Methods: A cross-sectional correlation study design...
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The Therapeutic Effects of Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Scleroderma

Yu Y, Shen L, Xie X, Zhao J, Jiang M

BACKGROUND: Scleroderma is a multisystem disease in which tissue fibrosis is caused by inflammation and vascular damage. The mortality of scleroderma has remained high due to a lack of effective...
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Metabolism and excretion of novel pulmonary-targeting docetaxel liposome in rabbits

Wang J, Zhang L, Wang L, Liu Z, Yu Y

Our study aims to determine the metabolism and excretion of novel pulmonary-targeting docetaxel liposome (DTX-LP) using the in vitro and in vivo animal experimental models. The metabolism and excretion of...
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RAR-Related Orphan Receptor: An Accelerated Preeclampsia Progression by Activating the JAK/STAT3 Pathway

Yu Y, Zhu T

Purpose: To investigate the effect and underlying mechanism of RAR related orphan receptor A (RORA) on preeclampsia (PE). Materials and Methods: Differentially expressed genes (DEGs) in four datasets were obtained by...
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