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Acute Abdominal Pain due to Accessory Splenic Infarction in an Adult: A Case Report

Wang H, So H, Nah YW, Kim M, Lee TY, Seo M, Bang SJ

Accessory spleens are common congenital anatomic variations that are usually asymptomatic. On the other hand, they can be clinically significant if complicated by hemorrhage, torsion, or infarction. This paper describes...
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The Positive Association between Subclinical Hypothyroidism and Newly-Diagnosed Hypertension Is More Explicit in Female Individuals Younger than 65

Wang X, Wang H, Yan L, Yang L, Xue Y, Yang J, Yao Y, Tang X, Tong N, Wang G, Zhang J, Wang Y, Ba J, Chen B, Du J, He L, Lai X, Li Y, Yan Z, Liao E, Liu C, Liu L, Qin G, Qin Y, Quan H, Shi B, Sun H, Ye Z, Zhang Q, Zhang L, Zhu J, Zhu M, Li Y, Teng W, Shan Z

Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controversial. The aim of the study was to analyze the association...
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Galectin-3 Derived from HucMSC Exosomes Promoted Myocardial Fibroblast-to-Myofibroblast Differentiation Associated with β-catenin Upregulation

Guo Q, Zhao Y, Li J, Huang C, Wang H, Zhao X, Wang M, Zhu W

Background and Objectives: Galectin-3 promotes fibroblast-to-myofibroblast differentiation and facilitates injury repair. Previous studies have shown that exosomes derived from human umbilical cord mesenchymal stem cells (hucMSC-ex) promote the differentiation of...
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The Role of miR-34c-5p in Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells

Liu B, Gan W, Jin Z, Wang M, Cui G, Zhang H, Wang H

Background and Objectives: Osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a critical role in the success of lumbar spinal fusion with autogenous bone graft. This study aims...
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Discontinuation Rate of Newly Prescribed Donepezil in Alzheimer’s Disease Patients in Asia

Park KH, Yang Y, Chen C, Shim YS, Dominguez JC, Lee CN, Kang K, Kim HJ, Jeong SK, Jeong JH, Hong Z, Yoon SJ, Zhang ZX, Kim EJ, Jang JW, Li Y, Xu Y, Lin YT, Qu Q, Hu CJ, Chou CH, Fan D, Kandiah N, Yang YH, Lau Ci, Chu LW, Wang H, Jung S, Choi SH, Kim S

Background and Purpose The rate of donepezil discontinuation and the underlying reasons for discontinuation in Asian patients with Alzheimer’s disease (AD) are currently unknown. We aimed to determine the treatment...
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Human Pneumonia Caused by Bordetella hinzii: First Case in Asia and Literature Review

Chen D, Wang H, Lu X, Cui Y, Ma X, Lou J, Zhou H

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Characterization of Brain Microstructural Abnormalities in High Myopia Patients: A Preliminary Diffusion Kurtosis Imaging Study

Wang H, Wen H, Li J, Chen Q, Li S, Wang Y, Wang Z

Objective: To evaluate microstructural damage in high myopia (HM) patients using 3T diffusion kurtosis imaging (DKI). Materials and Methods: This prospective study included 30 HM patients and 33 age- and sex-matched...
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Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway

Wang H, Shi X, Cheng L, Han J, Mu J

The present study explored the therapeutic potential of hydrogen sulfide (H2 S) in restoring aging-induced loss of cardioprotective effect of remote ischemic preconditioning (RIPC) along with the involvement of signaling...
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Excessive copper in feed not merely undermines animal health but affects food safety

Ma Z, Li Y, Han Z, Liu Z, Wang H, Meng F, Liu S, Chen D, Liu M

Background: Blackened intestines in slaughtered pigs have been commonly observed in China in recent years. However, no cause has been reported. Objectives: We attempted to determine whether the blackening of the...
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Development and Validation of the Humanistic Practice Ability of Nursing Scale

Zhang J, Zhou X, Wang H, Luo Y, Li W

Purpose: The purpose of this study was to develop a Humanistic Practice Ability of Nursing (HPAN) scale adapted to China and validate its psychometric properties. Methods: The original HPAN scale was...
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Inhibition of Long Noncoding RNA SNHG15 Ameliorates Hypoxia/Ischemia-Induced Neuronal Damage by Regulating miR-302a-3p/STAT1/NF-κB Axis

Hu C, Li C, Ma Q, Wang R, He Y, Wang H, Luo G

Purpose: Ischemic brain injury results in high mortality and serious neurologic morbidity. Here, we explored the role of SNHG15 in modulating neuronal damage and microglial inflammation after ischemia stroke. Materials and...
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Association between burnout and wellness culture among emergency medicine providers

Jyothindran R, d’Etienne JP, Marcum K, Ho AF, Robinson RD, Tijerina A, Graca C, Knowles HC, Zenarosa NR, Wang H

Objective Burnout is a common occurrence among healthcare providers and has been associated with provider wellness culture. However, this association has not been extensively studied among emergency medicine (EM) providers....
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Regulation of Gut Microbiota Disrupts the Glucocorticoid Receptor Pathway and Inflammation-related Pathways in the Mouse Hippocampus

Rao X, Liu L, Wang H, Yu Y, Li W, Chai T, Zhou W, Ji P, Song J, Wei H, Xie P

An increasing number of studies have recently indicated the important effects of gut microbes on various functions of the central nervous system. However, the underlying mechanisms by which gut microbiota regulate...
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Maxillary protraction using customized mini-plates for anchorage in an adolescent girl with skeletal Class III malocclusion

Liang S, Xie X, Wang F, Chang Q, Wang H, Bai Y

The treatment of skeletal Class III malocclusion in adolescents is challenging. Maxillary protraction, particularly that using bone anchorage, has been proven to be an effective method for the stimulation of maxillary...
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Exploring the role and mechanisms of diallyl trisulfide and diallyl disulfide in chronic constriction-induced neuropathic pain in rats

Wang G, Yang Y, Wang C, Huang J, Wang X, Liu Y, Wang H

Background: Garlic oil is a rich source of organosulfur compounds including diallyl disulfide and diallyl trisulfide. There have been studies showing the neuroprotective actions of these organosulfur compounds. However, the...
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Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway

Jin Y, Wang H, Li J, Dang M, Zhang W, Lei Y, Zhao H

In the present experimental study, cecal ligation and puncture significantly increased the myocardial injury assessed in terms of excess release of creative kinase-MB (CK-MB), cardiac troponin I (cTnI), interleukin (IL)-6...
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Prognostic Value of TP53 Mutation for Transcatheter Arterial Chemoembolization Failure/Refractoriness in HBV-Related Advanced Hepatocellular Carcinoma

Xue M, Wu Y, Fan W, Guo J, Wei J, Wang H, Tan J, Wang Y, Yao W, Zhao Y, Li J

Purpose This study aimed to investigate the clinicopathologic features and mutational landscape of patients with hepatitis B virus (HBV)–related advanced hepatocellular carcinomas (HCC) undergoing transcatheter arterial chemoembolization (TACE). Materials and Methods From January...
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Comparison of the Distribution Pattern of 21-Gene Recurrence Score between Mucinous Breast Cancer and Infiltrating Ductal Carcinoma in Chinese Population: A Retrospective Single-Center Study

Wu J, Ding S, Lin L, Fei X, Lin C, Andriani L, Goh C, Huang J, Hong J, Gao W, Zhu S, Wang H, Huang O, Chen X, He J, Li Y, Shen K, Chen W, Zhu L

Purpose This retrospective study aimed to evaluate the distribution pattern and prognostic value of 21-gene recurrence score (RS) in Chinese patients with mucinous breast cancer (MC) and compared with infiltrating ductal...
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Hyperinsulinemic Hypoglycemia after Bariatric Surgery

Hu S, Tang H, Wang H, Dong Z, Jiang S, Wang C, Chen X, Yang W

Postprandial hyperinsulinemic hypoglycemia (PHH) is one of the serious complications after bariatric surgery, it can lead life-threatening neuroglycopenic symptoms, such as seizures, disorientation, impairment of version and loss of consciousness...
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Epidemiological investigation of porcine pseudorabies virus and its coinfection rate in Shandong Province in China from 2015 to 2018

Ma Z, Han Z, Liu Z, Meng F, Wang H, Cao L, Li Y, Jiao Q, Liu S, Liu M

Background: Pseudorabies, also known as Aujeszky's disease, is caused by the pseudorabies virus (PRV) and has been recognized as a critical disease affecting the pig industry and a wide range...
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