- Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib
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Kang D, Han Z, Oh GH, Joo Y, Choi HJ, Song JJ
- KMID: 2418924
- Yonsei Med J.
- 2017 Sep;58(5):899-909.
- doi: 10.3349/ymj.2017.58.5.899
PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism... -
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- Catheter Ablation of Atrial Fibrillation Raises the Plasma Level of NGF-beta Which Is Associated with Sympathetic Nerve Activity
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Park JH, Hong SY, Wi J, Lee DL, Joung B, Lee MH, Pak HN
- KMID: 2345879
- Yonsei Med J.
- 2015 Nov;56(6):1530-1537.
- doi: 10.3349/ymj.2015.56.6.1530
PURPOSE: The expression of nerve growth factor-beta (NGF-beta) is related to cardiac nerve sprouting and sympathetic hyper innervation. We investigated the changes of plasma levels of NGF-beta and the relationship... -
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- TGF-beta Mediated Epithelial-Mesenchymal Transition in Autosomal Dominant Polycystic Kidney Disease
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Chea SW, Lee KB
- KMID: 1782975
- Yonsei Med J.
- 2009 Feb;50(1):105-111.
- doi: 10.3349/ymj.2009.50.1.105
PURPOSE: Recent studies have showed that epithelial-mesenchymal transition (EMT) is a key process of glomerular and tubulointerstitial pathology in many chronic kidney diseases. However, there are no data of EMT... -
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- Transforming Growth Factor-beta Levels in Human Aqueous Humor of Glaucomatous, Diabetic and Uveitic Eyes
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Min SH, Lee TI, Chung YS, Kim HK
- KMID: 754573
- Korean J Ophthalmol.
- 2006 Sep;20(3):162-165.
- doi: 10.3341/kjo.2006.20.3.162
PURPOSE: Transforming growth factor-beta2 is known to be present at elevated levels in the aqueous humor of patients with primary open angle glaucoma (POAG) and diabetes but not in... -
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- HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1
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Shin JY, Hur W, Wang JS, Jang JW, Kim CW, Bae SH, Jang SK, Yang SH, Sung YC, Kwon OJ, Yoon SK
- KMID: 755753
- Exp Mol Med.
- 2005 Apr;37(2):138-145.
Liver cirrhosis is one of the major complications of hepatitis C virus (HCV) infection, but the mechanisms underlying HCV-related fibrogenesis are still not clear. Although the roles of HCV core... -
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- Differential Expression of TGF-beta Isoforms During Differentiation of HaCaT Human Keratinocyte Cells: Implication for the Separate Role in Epidermal Differentiation
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Cho HR, Hong SB, Kim YI, Lee JW, Kim NI
- KMID: 1778568
- J Korean Med Sci.
- 2004 Dec;19(6):853-858.
- doi: 10.3346/jkms.2004.19.6.853
The three mammalian isoforms of transforming growth factor-beta (TGF-beta1, beta2, beta3) are potent regulators of cell growth, differentiation, and extracellular matrix deposition. To study their role in skin differentiation, we... -
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